Piotrowski Michał, Maras Piotr, Stempień Zbigniew, Wach Radosław, Kozicki Marek
Department of Mechanical Engineering, Informatics and Chemistry of Polymer Materials, Faculty of Materials Technologies and Textile Design, Lodz University of Technology, 90-543 Lodz, Poland.
Department of Radiotherapy Planning, Copernicus Hospital, 93-513 Lodz, Poland.
Materials (Basel). 2025 Jul 2;18(13):3135. doi: 10.3390/ma18133135.
This work presents a Fricke radiochromic gel dosimeter with xylenol orange (XO) and a gelatin matrix modified with sorbitol. The dosimeter, combined with 2D scanning using a flatbed scanner and data processing using dedicated software packages, creates a radiotherapy dosimetry measurement system. The dosimeter reacts to ionizing radiation by changing color as a result of the formation of complexes of Fe and XO molecules. It was characterized in terms of thermal and chemical stability and mechanical properties. The presence of sorbitol improved the mechanical and thermal properties of the dosimeter. The dosimeter maintains chemical stability, enabling its use in dosimetric applications, for at least six weeks. The dose-response characteristics of the dosimeter are discussed and indicate a dynamic dose-response of the dosimeter (up to saturation) of about 20 Gy and a linear dose-response of about 12.5 Gy. The following applications of the dosimeter are discussed: (i) as a 2D dosimeter in a plastic container for performing a coincidence test of radiation and mechanical isocenters of a medical accelerator, and (ii) for dosimetry as a 2D dosimeter alone and simultaneously as a bolus and a 2D dosimeter. Research has shown that the dosimeter has promise in many applications.
这项工作展示了一种含有二甲酚橙（XO）和经山梨醇改性的明胶基质的弗里克放射变色凝胶剂量计。该剂量计与使用平板扫描仪的二维扫描以及使用专用软件包的数据处理相结合，创建了一个放射治疗剂量测定测量系统。该剂量计通过铁和XO分子形成络合物而变色，从而对电离辐射作出反应。对其热稳定性、化学稳定性和机械性能进行了表征。山梨醇的存在改善了剂量计的机械性能和热性能。该剂量计保持化学稳定性，使其能够在剂量测定应用中使用至少六周。讨论了该剂量计的剂量响应特性，结果表明该剂量计的动态剂量响应（直至饱和）约为20 Gy，线性剂量响应约为12.5 Gy。讨论了该剂量计的以下应用：（i）作为塑料容器中的二维剂量计，用于进行医用加速器辐射等中心和机械等中心的重合测试；（ii）单独作为二维剂量计，同时作为推注器和二维剂量计进行剂量测定。研究表明，该剂量计在许多应用中具有前景。
