Department of Anesthesiology, Critical Care and Pain, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, Maharashtra, India.
Intensive Care Unit, Cabrini Hospital, Malvern, Victoria, Australia. Central Clinical School, Faculty of Medicine, Monash University, Melbourne, Victoria, Australia.
Curr Opin Anaesthesiol. 2022 Apr 1;35(2):115-121. doi: 10.1097/ACO.0000000000001102.
The physiologically difficult airway is one in which physiologic alterations in the patient increase the risk for cardiorespiratory and other complications during tracheal intubation and transition to positive pressure ventilation. This review will summarize the recent literature around the emerging concept of the physiologically difficult airway, describe its relevance and various patient types in which this entity is observed.
Physiologic derangements during airway management occur due acute illness, pre-existing disease, effects of anesthetic agents, and positive pressure ventilation. These derangements are especially recognized in critically ill patients, but can also occur in otherwise healthy patients including obese, pregnant and pediatric patients who have certain physiological alterations. Critically ill patients may have a physiologically difficult airway due to the presence of acute respiratory failure, hypoxemia, hypotension, severe metabolic acidosis, right ventricular failure, intracranial hypertension, and risk of aspiration of gastric contents during tracheal intubation.
Understanding the physiological alterations and the risks involved in patients with a physiologically difficult airway is necessary to optimize the physiology and adopt strategies to avoid complications during tracheal intubation. Further research will help us better understand the optimal strategies to improve outcomes in these patients.
生理困难气道是指患者在气管插管和过渡到正压通气期间,由于生理改变增加了心肺等并发症风险的气道。本文将总结生理困难气道这一新兴概念的最新文献,描述其相关性和观察到的各种患者类型。
气道管理期间的生理紊乱是由于急性疾病、先前存在的疾病、麻醉剂的作用以及正压通气引起的。这些紊乱在危重病患者中尤为明显,但也可能发生在其他健康患者中,包括肥胖、妊娠和儿科患者,他们存在某些生理改变。危重病患者可能由于急性呼吸衰竭、低氧血症、低血压、严重代谢性酸中毒、右心衰竭、颅内压升高以及在气管插管期间胃内容物吸入的风险而存在生理困难气道。
了解生理困难气道患者的生理改变和相关风险对于优化生理学并采取策略避免气管插管期间的并发症是必要的。进一步的研究将帮助我们更好地理解改善这些患者结局的最佳策略。