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基于房颤患者偶然诊断出心房黏液瘤及疑似卡尼综合征的病例报告

A Case Presentation Based on Incidental Diagnosis of Atrial Myxoma in a Patient Presenting With Atrial Fibrillation and Suspected Carney Complex.

作者信息

Khan Zahid, Pabani Umesh Kumar, Gupta Animesh, Lohano Sunaina, Mlawa Gideon

机构信息

Cardiology, Royal Free Hospital, London, GBR.

Internal Medicine, Barking, Havering and Redbridge University Hospitals National Health Services Trust, London, GBR.

出版信息

Cureus. 2022 Jan 12;14(1):e21157. doi: 10.7759/cureus.21157. eCollection 2022 Jan.

DOI:10.7759/cureus.21157
PMID:35165607
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8831319/
Abstract

We present the case of a 54-year-old lady who presented to hospital with palpitations and was diagnosed with atrial fibrillation with rapid ventricular response. She was given intravenous metoprolol 5 mg initially followed by a further 5 mg and was commenced on bisoprolol 2.5 mg once daily. She reverted back to normal sinus rhythm and was referred for echocardiography following an episode of paroxysmal atrial fibrillation. The echocardiogram showed a large mobile atrial myxoma in the left atrium and mild-to-moderate mitral regurgitation with preserved left ventricular function. Her past medical history includes transsphenoidal surgery for acromegaly in 1979, followed by radiotherapy and partial thyroidectomy for goitre. Her chest radiograph was normal and blood results were unremarkable. She was accepted for inpatient transfer to a cardiothoracic centre for surgical removal of atrial myxoma. She underwent surgery with successful excision of the atrial myxoma, and biopsies confirmed the mass to be atrial myxoma. The surgery was complicated by the patient developing atrial fibrillation with fast ventricular response that was chemically cardioverted with an intravenous loading dose of amiodarone 300 mg over 2 hours followed by 900 mg infusion over 24 hours. She had follow-up in the outpatient clinic with cardiology and endocrine specialists for a year and no recurrence of myxoma was noted. Her blood tests including growth hormone and thyroid function tests were normal.

摘要

我们报告了一例54岁女性患者,她因心悸入院,被诊断为伴有快速心室反应的心房颤动。最初给予她静脉注射美托洛尔5毫克,随后再注射5毫克,并开始每日服用比索洛尔2.5毫克。她恢复为正常窦性心律,在一次阵发性心房颤动发作后被转诊进行超声心动图检查。超声心动图显示左心房有一个巨大的可移动心房黏液瘤,伴有轻度至中度二尖瓣反流,左心室功能保留。她的既往病史包括1979年因肢端肥大症接受经蝶窦手术,随后因甲状腺肿接受放疗和部分甲状腺切除术。她的胸部X光片正常,血液检查结果无异常。她被收治住院,转至心胸外科中心进行心房黏液瘤的手术切除。她接受了手术,成功切除了心房黏液瘤,活检证实肿块为心房黏液瘤。手术出现并发症,患者发生伴有快速心室反应的心房颤动,通过静脉注射300毫克胺碘酮负荷剂量在2小时内进行化学复律,随后在24小时内输注900毫克。她在门诊接受了心脏病学和内分泌专家的随访一年,未发现黏液瘤复发。她的血液检查,包括生长激素和甲状腺功能检查均正常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f56e/8831319/880ba1551a74/cureus-0014-00000021157-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f56e/8831319/4176722006de/cureus-0014-00000021157-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f56e/8831319/fe641cb52f56/cureus-0014-00000021157-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f56e/8831319/880ba1551a74/cureus-0014-00000021157-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f56e/8831319/4176722006de/cureus-0014-00000021157-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f56e/8831319/fe641cb52f56/cureus-0014-00000021157-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f56e/8831319/880ba1551a74/cureus-0014-00000021157-i03.jpg

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