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英格兰自杀身亡者中的自闭症及自闭症特质。

Autism and autistic traits in those who died by suicide in England.

作者信息

Cassidy Sarah, Au-Yeung Sheena, Robertson Ashley, Cogger-Ward Heather, Richards Gareth, Allison Carrie, Bradley Louise, Kenny Rebecca, O'Connor Rory, Mosse David, Rodgers Jacqui, Baron-Cohen Simon

机构信息

School of Psychology, University of Nottingham, UK and Faculty of Health and Life Sciences, Coventry University, UK.

School of Psychology, University of Nottingham, UK, Faculty of Health and Life Sciences, Coventry University, UK and Department of Psychiatry, University of Oxford, UK.

出版信息

Br J Psychiatry. 2022 Feb 15:1-9. doi: 10.1192/bjp.2022.21.

Abstract

BACKGROUND

Autism and autistic traits are risk factors for suicidal behaviour.

AIMS

To explore the prevalence of autism (diagnosed and undiagnosed) in those who died by suicide, and identify risk factors for suicide in this group.

METHOD

Stage 1: 372 coroners' inquest records, covering the period 1 January 2014 to 31 December 2017 from two regions of England, were analysed for evidence that the person who died had diagnosed autism or undiagnosed possible autism (elevated autistic traits), and identified risk markers. Stage 2: 29 follow-up interviews with the next of kin of those who died gathered further evidence of autism and autistic traits using validated autism screening and diagnostic tools.

RESULTS

Stage 1: evidence of autism (10.8%) was significantly higher in those who died by suicide than the 1.1% prevalence expected in the UK general alive population (odds ratio (OR) = 11.08, 95% CI 3.92-31.31). Stage 2: 5 (17.2%) of the follow-up sample had evidence of autism identified from the coroners' records in stage 1. We identified evidence of undiagnosed possible autism in an additional 7 (24.1%) individuals, giving a total of 12 (41.4%); significantly higher than expected in the general alive population (1.1%) (OR = 19.76, 95% CI 2.36-165.84). Characteristics of those who died were largely similar regardless of evidence of autism, with groups experiencing a comparably high number of multiple risk markers before they died.

CONCLUSIONS

Elevated autistic traits are significantly over-represented in those who die by suicide.

摘要

背景

自闭症及自闭症特质是自杀行为的风险因素。

目的

探讨自杀身亡者中自闭症(已确诊和未确诊)的患病率,并确定该群体中自杀的风险因素。

方法

第一阶段:分析了2014年1月1日至2017年12月31日来自英格兰两个地区的372份死因裁判记录,以寻找死者患有已确诊自闭症或未确诊的可能自闭症(自闭症特质升高)的证据,并确定风险标志物。第二阶段:对死者近亲进行了29次随访访谈,使用经过验证的自闭症筛查和诊断工具收集了更多关于自闭症和自闭症特质的证据。

结果

第一阶段:自杀身亡者中自闭症的证据(10.8%)显著高于英国一般在世人群预期的1.1%患病率(优势比(OR)=11.08,95%置信区间3.92 - 31.31)。第二阶段:随访样本中有5人(17.2%)在第一阶段的死因裁判记录中发现有自闭症证据。我们在另外7人(24.1%)中发现了未确诊的可能自闭症证据,总计12人(41.4%);显著高于一般在世人群的预期(1.1%)(OR = 19.76,95%置信区间2.36 - 165.84)。无论有无自闭症证据,死者的特征基本相似,两组在死亡前都经历了相当多的多种风险标志物。

结论

自闭症特质升高在自杀身亡者中显著超比例存在。

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