蛙皮素对人体胰岛素及胃泌素对食物反应的相反作用。
Opposite effects of bombesin on insulin and gastrin response to food in humans.
作者信息
Scarpignato C, Micali B
出版信息
Gut. 1986 May;27(5):499-504. doi: 10.1136/gut.27.5.499.
Abstract
The effect of bombesin on insulin and gastrin response to a standard labelled meal was studied in eight healthy male volunteers. The gastric emptying of solids was simultaneously evaluated. During intravenous infusion of the peptide (5 ng/kg/min) the insulin release after eating was greatly reduced whereas food stimulated gastrin release was significantly enhanced. Both effects of bombesin are likely to be connected with the marked inhibition of gastric emptying induced by the peptide.
摘要
在8名健康男性志愿者中研究了蛙皮素对胰岛素和胃泌素对标准标记餐反应的影响。同时评估了固体食物的胃排空情况。在静脉输注该肽（5纳克/千克/分钟）期间，进食后胰岛素释放大幅减少，而食物刺激的胃泌素释放显著增强。蛙皮素的这两种作用可能都与该肽引起的胃排空明显抑制有关。
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本文引用的文献
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Immunoassay of insulin with insulin-antibody precipitate.用胰岛素 - 抗体沉淀物进行胰岛素免疫测定。
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Down with multiple t-tests.摒弃多重t检验。
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Mechanisms of gastrin release by bombesin and food.蛙皮素和食物引起胃泌素释放的机制。
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Comparison of four different algorithms for the calculation of radioimmunoassay standard curves.四种不同算法用于放射免疫分析标准曲线计算的比较。
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High potency of bombesin for stimulation of human gastrin release and gastric acid secretion.蛙皮素对刺激人胃泌素释放和胃酸分泌具有高效能。
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Inhibition of gastric emptying by bombesin in man.蛙皮素对人体胃排空的抑制作用。
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8
Bombesin: action on gut hormones and calcium in man.蛙皮素：对人体肠道激素和钙的作用
J Clin Endocrinol Metab. 1982 May;54(5):980-5. doi: 10.1210/jcem-54-5-980.
9
Gastric emptying as a determinant of the oral glucose tolerance test.胃排空作为口服葡萄糖耐量试验的一个决定因素。
Gastroenterology. 1982 Jan;82(1):51-5.
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Effects of caerulein and bombesin on insulin and glucagon secretion from the isolated, perfused rat pancreas.蛙皮素和铃蟾肽对离体灌注大鼠胰腺胰岛素和胰高血糖素分泌的影响。
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