Social Determinants of Health Research Center, School of Allied Medical Sciences, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Department of Medical Physics and Radiology, School of allied medical sciences, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Przegl Epidemiol. 2021;75(3):326-331. doi: 10.32394/pe.75.29.
The Coronavirus disease 2019 (COVID-19) outbreak is an increasing major global public health threat. Mortality rate varies across countries, therefore conducting studies on this disease in different countries is necessary, and will improve disease management worldwide.
This study aimed to investigate the COVID-19 disease course characteristics in Iran.
This is a retrospective study of 108 patients with confirmed COVID-19 from Feb 20 to June 20, 2020, at one Hospital in Iran. In summary, we obtained demographic data, clinical, laboratory, and chest CT findings of patients. The statistical analysis evaluated patients in two groups: recovered or died.
In brief, cough (70/108, 64.8%) and fever (69/108, 63.9%) were the most common symptoms. CT scan findings of patients with COVID-19 showed that bilateral lung involvement was more common in deceased patients than recovered ones (20/26, 76.9% vs. 30/70, 42.8%, p = 0.026). Laboratory findings of routine blood tests including Erythrocyte sedimentation rate (ESR), Fasting Blood Sugar (FBS), White Blood Cell (WBC), the number of platelets (PLTs) showed a significant difference between the two groups (p <0.05). There were no significant differences in age and gender between the two groups.
In this study, we described the features of deceased and recovered patients with COVID-19. Our findings suggest that levels of FBS, ESR, WBC, and PLTs, also patterns of lung involvement, existence of underlying disease, respiratory rate, and oxygen saturation can be predictors of mortality risk. Further studies are proposed to investigate these characteristics in different populations.
2019 年冠状病毒病（COVID-19）疫情是日益严重的全球主要公共卫生威胁。死亡率因国家而异，因此有必要在不同国家对该病进行研究，从而改善全球疾病管理。
本研究旨在调查伊朗 COVID-19 疾病的病程特征。
这是一项回顾性研究，纳入了 2020 年 2 月 20 日至 6 月 2 日期间伊朗某医院的 108 例确诊 COVID-19 患者。总之，我们获得了患者的人口统计学数据、临床、实验室和胸部 CT 结果。统计分析将患者分为两组：康复或死亡。
简而言之，咳嗽（70/108，64.8%）和发热（69/108，63.9%）是最常见的症状。COVID-19 患者的 CT 扫描结果显示，死亡患者双侧肺部受累比康复患者更常见（20/26，76.9%比 30/70，42.8%，p=0.026）。常规血液检查的实验室结果包括红细胞沉降率（ESR）、空腹血糖（FBS）、白细胞（WBC）、血小板（PLT）计数在两组之间存在显著差异（p<0.05）。两组间在年龄和性别上无显著差异。
本研究描述了 COVID-19 死亡和康复患者的特征。我们的研究结果表明，FBS、ESR、WBC、PLT 水平、肺部受累模式、基础疾病存在、呼吸频率和血氧饱和度可能是死亡风险的预测指标。建议进一步研究不同人群的这些特征。
