Department of Infectious Diseases, School of Medicine, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Rom J Intern Med. 2020 Dec 17;58(4):242-250. doi: 10.2478/rjim-2020-0019. Print 2020 Dec 1.
Coronavirus disease 2019 (COVID-19) was initially detected in Wuhan city, China. Chest CT features of COVID-19 pneumonia have been investigated mostly in China, and there is very little information available on the radiological findings occurring in other populations. In this study, we aimed to describe the characteristics of chest CT findings in confirmed cases of COVID-19 pneumonia in an Iranian population, based on a time classification. Eighty-nine patients with COVID-19 pneumonia, confirmed by a real-time RT-PCR test, who were admitted to non-ICU wards and underwent a chest CT scan were retrospectively enrolled. Descriptive evaluation of radiologic findings was performed using a classification based on the time interval between the initiation of the symptoms and chest CT-scan. The median age of patients was 58.0 years, and the median time interval from the onset of symptoms to CT scan evaluation was 7 days. Most patients had bilateral (94.4%) and multifocal (91.0%) lung involvement with peripheral distribution (60.7%). Also, most patients showed involvement of all five lobes (77.5%). Ground-glass opacities (GGO) (84.3%) and mixed GGO with consolidation (80.9%) were the most common identified patterns. We also found that as the time interval between symptoms and CT scan evaluation increased, the predominant pattern changed from GGO to mixed pattern and then to elongated-containing and band-like-opacities-containing pattern; on the other hand, the percentage of lung involvement increased. Bilateral multifocal GGO, and mixed GGO with consolidation were the most common patterns of COVID-19 pneumonia in our study. However, these patterns might change according to the time interval from symptoms.
2019 年冠状病毒病(COVID-19)最初在中国武汉市被发现。中国对 COVID-19 肺炎的胸部 CT 特征进行了大量研究,而关于其他人群中发生的放射学发现的信息却很少。在这项研究中,我们旨在根据时间分类,描述伊朗人群中确诊 COVID-19 肺炎的胸部 CT 表现特征。我们回顾性地招募了 89 例经实时 RT-PCR 检测确诊为 COVID-19 肺炎的患者,这些患者被收入非 ICU 病房并接受了胸部 CT 扫描。使用基于症状发作和胸部 CT 扫描之间时间间隔的分类对放射学发现进行描述性评估。患者的中位年龄为 58.0 岁,从症状发作到 CT 扫描评估的中位时间间隔为 7 天。大多数患者的肺部受累呈双侧(94.4%)和多灶性(91.0%)分布,以周边为主(60.7%)。此外,大多数患者均累及所有五个肺叶(77.5%)。磨玻璃影(GGO)(84.3%)和混合 GGO 伴实变(80.9%)是最常见的表现类型。我们还发现,随着症状和 CT 扫描评估之间的时间间隔增加,主要表现从 GGO 转变为混合模式,然后转变为拉长样和带状样实变模式;另一方面,肺部受累的百分比增加。双侧多灶性 GGO 和混合 GGO 伴实变是我们研究中 COVID-19 肺炎最常见的表现类型。然而,这些表现类型可能会根据症状出现的时间间隔而发生变化。