• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

夜间型作为重性抑郁障碍患者的双相特征之一：一项初步因子分析的结果。

Evening chronotype as a bipolar feature among patients with major depressive disorder: the results of a pilot factor analysis.

机构信息

Department of Clinical Pharmacology, Medical University of Lodz, Lodz, Poland.

Department of Clinical Psychology and Psychopathology, Institute of Psychology, University of Lodz, Lodz, Poland.

出版信息

Braz J Psychiatry. 2022 Jan-Feb;44(1):35-40. doi: 10.1590/1516-4446-2021-1747.

DOI:10.1590/1516-4446-2021-1747
PMID:35170673
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8827374/
Abstract

OBJECTIVES

The bipolar spectrum concept has resulted in a paradigm shift that has affected both the diagnosis and therapy of mood disorders, with bipolarity becoming an indicator of treatment resistance in depression. Evening circadian preference has also been linked to affective disorders. The aim of our study was to confirm the relationship between the severity of depressive symptoms, bipolar features, chronotype, and sleep quality among patients with major depressive disorder.

METHODS

A group of 55 individuals who were recruited from a mental health outpatient clinic completed the following psychometric tools: a Chronotype Questionnaire comprising morningness-eveningness (ME) and subjective amplitude of the rhythm (AM) scales, the Hypomania Checklist 32 (HCL-32), the Beck Depression Inventory (BDI) and the Pittsburgh Sleep Quality Index (PSQI).

RESULTS

Factor analysis identified two latent components, accounting cumulatively for 58% of variables: depressive symptoms (BDI and PSQI) and bipolarity (ME, AM, and HCL-32). After rotation, ME loading in the first factor increased the result to a significant level. The correlation between the two components was very low.

CONCLUSIONS

Evening chronotype appears to be a bipolarity-related marker, with this relationship being independent of its link to depressive symptoms and sleep quality. Eveningness and high circadian rhythm amplitude may offer promise as diagnostic, prognostic, and therapeutic predictors.

摘要

目的

双相谱概念带来了一种范式转变，不仅影响了心境障碍的诊断和治疗，而且双相性也成为抑郁症治疗抵抗的一个指标。夜间生理节奏偏好也与情感障碍有关。我们的研究目的是确认重度抑郁症患者的抑郁症状严重程度、双相特征、昼夜类型和睡眠质量之间的关系。

方法

一组 55 名从精神科门诊招募的患者完成了以下心理计量学工具：包含晨型-晚型（ME）和节律主观幅度（AM）量表的昼夜类型问卷、32 项轻躁狂检查表（HCL-32）、贝克抑郁量表（BDI）和匹兹堡睡眠质量指数（PSQI）。

结果

因子分析确定了两个潜在的成分，累计占变量的 58%：抑郁症状（BDI 和 PSQI）和双相性（ME、AM 和 HCL-32）。经旋转后，第一个因子中的 ME 负荷增加到显著水平。两个成分之间的相关性非常低。

结论

夜间昼夜类型似乎是与双相性相关的标志物，这种关系与抑郁症状和睡眠质量无关。夜间型和高生理节奏幅度可能成为诊断、预后和治疗的预测指标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65fb/8827374/30836f6e2e3a/bjp-44-01-35-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65fb/8827374/338264f53f94/bjp-44-01-35-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65fb/8827374/30836f6e2e3a/bjp-44-01-35-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65fb/8827374/338264f53f94/bjp-44-01-35-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65fb/8827374/30836f6e2e3a/bjp-44-01-35-g002.jpg

相似文献

1
Evening chronotype as a bipolar feature among patients with major depressive disorder: the results of a pilot factor analysis.夜间型作为重性抑郁障碍患者的双相特征之一：一项初步因子分析的结果。
Braz J Psychiatry. 2022 Jan-Feb;44(1):35-40. doi: 10.1590/1516-4446-2021-1747.
2
Sleep quality, chronotype, temperament and bipolar features as predictors of depressive symptoms among medical students.医学生的睡眠质量、昼夜节律类型、气质和双相特征作为抑郁症状的预测因素
Chronobiol Int. 2017;34(6):708-720. doi: 10.1080/07420528.2017.1316730. Epub 2017 May 10.
3
Patterns of self-reported depressive symptoms in relation to morningness-eveningness in inpatients with a depressive disorder.抑郁障碍住院患者自述抑郁症状与晨型-晚型的关系模式。
Psychiatry Res. 2016 May 30;239:163-8. doi: 10.1016/j.psychres.2016.03.018. Epub 2016 Mar 10.
4
Validation of the 6-item Evening Chronotype Scale (ECS): a modified version of Composite Scale Morningness.验证 6 项夜间时型量表（ECS）：复合量表晨型的修订版。
Chronobiol Int. 2021 Nov;38(11):1640-1649. doi: 10.1080/07420528.2021.1938596. Epub 2021 Aug 19.
5
The role of affective temperaments assessed by the Temperament Evaluation of Memphis, Pisa and San Diego-Autoquestionnaire (TEMPS-A) in the relationship between morningness-eveningness and bipolarity.由 Memphis、Pisa 和 San Diego 自动问卷（TEMPS-A）评估的情感气质在晨型-晚型与双相情感障碍之间关系中的作用。
J Affect Disord. 2018 May;232:83-88. doi: 10.1016/j.jad.2018.02.017. Epub 2018 Feb 16.
6
Chronotype and depressive symptoms in healthy subjects: the mediating role of hopelessness and subjective sleep quality.健康受试者的昼夜型与抑郁症状：无望感和主观睡眠质量的中介作用。
Chronobiol Int. 2020 Aug;37(8):1173-1180. doi: 10.1080/07420528.2020.1775629. Epub 2020 Jul 8.
7
Eveningness and poor sleep quality independently contribute to self-reported depression severity in psychiatric inpatients with affective disorder.在患有情感障碍的精神科住院患者中，晚睡倾向和睡眠质量差各自独立导致自我报告的抑郁严重程度。
Nord J Psychiatry. 2016 Jul;70(5):329-34. doi: 10.3109/08039488.2015.1112832. Epub 2015 Dec 4.
8
Eveningness is associated with more severe depressive symptoms independently of sleep quality and fatigue level only in first-episode but not recurrent depression in major depressive disorder.在单相抑郁障碍中，仅首发而非复发性抑郁中，与睡眠质量和疲劳水平无关，晨型与更严重的抑郁症状相关。
Chronobiol Int. 2024 Jul;41(7):987-995. doi: 10.1080/07420528.2024.2378958. Epub 2024 Jul 15.
9
Exploratory Study on the Associations between Lifetime Post-Traumatic Stress Spectrum, Sleep, and Circadian Rhythm Parameters in Patients with Bipolar Disorder.双相障碍患者一生中创伤后应激综合征、睡眠和昼夜节律参数之间关联的探索性研究。
Int J Environ Res Public Health. 2023 Feb 17;20(4):3566. doi: 10.3390/ijerph20043566.
10
Associations between chronotype, sleep quality, suicidality, and depressive symptoms in patients with major depression and healthy controls.在重性抑郁障碍患者和健康对照者中，睡眠时相、睡眠质量、自杀意念和抑郁症状之间的关联。
Chronobiol Int. 2010 Oct;27(9-10):1813-28. doi: 10.3109/07420528.2010.516380.

引用本文的文献

1
Factors associated with chronotype in individuals with bipolar disorder in remission.缓解期双相情感障碍患者的昼夜节律类型相关因素。
Indian J Psychiatry. 2025 Apr;67(4):419-427. doi: 10.4103/indianjpsychiatry.indianjpsychiatry_980_24. Epub 2025 Apr 15.
2
Disentangling the Genetic Landscape of Peripartum Depression: A Multi-Polygenic Machine Learning Approach on an Italian Sample.解析围产期抑郁症的遗传图谱：基于意大利样本的多基因机器学习方法
Genes (Basel). 2024 Nov 26;15(12):1517. doi: 10.3390/genes15121517.
3
The Mediation Effect of Peripheral Biomarkers of Calcium Metabolism and Chronotypes in Bipolar Disorder Psychopathology.

本文引用的文献

1
Chronotype and Social Jetlag: A (Self-) Critical Review.昼夜节律类型与社会时差：一篇（自我）批判性综述。
Biology (Basel). 2019 Jul 12;8(3):54. doi: 10.3390/biology8030054.
2
Global Burden of Disease and the Impact of Mental and Addictive Disorders.全球疾病负担与精神和成瘾性障碍的影响
Curr Psychiatry Rep. 2019 Feb 7;21(2):10. doi: 10.1007/s11920-019-0997-0.
3
Chronotype and Mental Health: Recent Advances.时型与心理健康：最新进展。
钙代谢外周生物标志物和昼夜节律类型在双相情感障碍精神病理学中的中介作用
Metabolites. 2022 Sep 2;12(9):827. doi: 10.3390/metabo12090827.
Curr Psychiatry Rep. 2018 Jul 23;20(8):59. doi: 10.1007/s11920-018-0925-8.
4
Evening types demonstrate reduced SSRI treatment efficacy.夜型人表现出较低的选择性5-羟色胺再摄取抑制剂（SSRI）治疗效果。
Chronobiol Int. 2018 Aug;35(8):1175-1178. doi: 10.1080/07420528.2018.1458316. Epub 2018 Apr 16.
5
The role of affective temperaments assessed by the Temperament Evaluation of Memphis, Pisa and San Diego-Autoquestionnaire (TEMPS-A) in the relationship between morningness-eveningness and bipolarity.由 Memphis、Pisa 和 San Diego 自动问卷（TEMPS-A）评估的情感气质在晨型-晚型与双相情感障碍之间关系中的作用。
J Affect Disord. 2018 May;232:83-88. doi: 10.1016/j.jad.2018.02.017. Epub 2018 Feb 16.
6
Morningness-Eveningness questionnaire in bipolar disorder.双相障碍的晨型-晚型问卷。
Psychiatry Res. 2018 Apr;262:102-107. doi: 10.1016/j.psychres.2018.02.004. Epub 2018 Feb 3.
7
The impact of affective temperaments on clinical and functional outcome of Bipolar I patients that initiated or changed pharmacological treatment for mania.情感气质对首发或更改药物治疗双相 I 型患者躁狂发作的临床和功能结局的影响。
Psychiatry Res. 2018 Mar;261:473-480. doi: 10.1016/j.psychres.2018.01.035. Epub 2018 Jan 31.
8
Chronotype description: In search of a solid subjective amplitude scale.昼夜节律类型描述：寻找一个可靠的主观振幅量表。
Chronobiol Int. 2017;34(10):1388-1400. doi: 10.1080/07420528.2017.1372469. Epub 2017 Nov 20.
9
Associations of depression and seasonality with morning-evening preference: Comparison of contributions of its morning and evening components.抑郁和季节性与早晚偏好的关联：早晚成分贡献的比较。
Psychiatry Res. 2018 Apr;262:609-617. doi: 10.1016/j.psychres.2017.09.054. Epub 2017 Sep 25.
10
State- and trait-like variation in morning and evening components of morningness-eveningness in winter depression.冬季抑郁症中晨型-夜型的早晨和晚上成分的状态性和特质性变化。
Nord J Psychiatry. 2017 Nov;71(8):561-569. doi: 10.1080/08039488.2017.1353642. Epub 2017 Jul 24.