稀释对坏死梭杆菌培养物感染性的不良影响。
The adverse effect of dilution on the infectivity of Fusobacterium necrophorum culture.
作者信息
Smith G R, Turner A
出版信息
J Hyg (Lond). 1986 Apr;96(2):199-203. doi: 10.1017/s0022172400065967.
Abstract
Dilution had an adverse effect on the infectivity of 24 h cultures of a strain of Fusobacterium necrophorum, which became apparent at or near the minimum lethal dose. Thus in mice inoculated subcutaneously the mortality produced by 0.01 ml of undiluted culture was almost invariably greater than that produced by 0.1 ml of a 1 in 10 dilution. The explanation appeared to lie in the increased physical separation of bacterial cells that was the inevitable consequence of dilution.
摘要
稀释对坏死梭杆菌菌株24小时培养物的感染性有不利影响，这在最低致死剂量或接近最低致死剂量时变得明显。因此，在皮下接种的小鼠中，0.01毫升未稀释培养物产生的死亡率几乎总是高于0.1毫升1:10稀释液产生的死亡率。其原因似乎在于稀释不可避免地导致细菌细胞物理分离增加。
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