Kibitov Andrey Alexandrovich, Rakitko Alexander Sergeevich, Kasyanov Evgeniy Dmitirevich, Rukavishnikov Grigoriy Viktorovich, Kozlova Kira Alexandrovna, Ilinsky Valeriy Vladimirovich, Neznanov Nikolay Grigor'evich, Mazo Galina Elevna, Kibitov Alexander Olegovich
V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology, Bekhtereva str., 3, Saint-Petersburg, Russia.
Genotek Ltd., Nastavnicheskiy Lane, 17-1, Moscow, Russia.
Clin Pract Epidemiol Ment Health. 2021 Dec 22;17:205-211. doi: 10.2174/1745017902117010205. eCollection 2021.
Web-based screening of depressive symptoms in general non-clinical population can provide better insights into actual prevalence of depressive symptoms and associated risk factors. To study the current prevalence of depressive symptoms in Russian non-clinical population we conducted screening using an online survey based on Depression subscale of Hospital Anxiety and Depression Scale (HADS-D).
The online survey covered 2610 Russian-speaking respondents and included HADS-D, questions about sex, age and presence of cardiovascular diseases (CVD) diagnoses or symptoms in respondents.
The proportion of respondents with depressive symptoms, estimated by online HADS-D, was 14.4% (11.5% - at subclinical level, 2.9% - at clinical level). The overall HADS-D score was higher in women (p=0.003), in young individuals under 30 y.o . participants over 42 y.o. (p=0.004) and in individuals with self-reported CVD symptoms (p=0.00002). Linear regression analysis showed that self-reported CVD symptoms increase HADS-D score (p<0.001), but male sex (p=0.002) and older age (p<0.001) decrease it. Logistic regression showed that CVD symptoms increase the risk of depressive symptoms by HADS-D (p=0.033, OR=1.29), but older age (p=0.015, OR=0.87) and male sex (as a trend, p=0.052, OR=0.80) decrease this risk.
Online survey based on HADS-D showed new patterns of depressive symptoms prevalence in Russian non-clinical population. Depressive symptoms prevalence did not differ between men and women and was higher among young people. The reported association between depressive symptoms and CVD was confirmed.
在一般非临床人群中基于网络筛查抑郁症状能够更好地洞察抑郁症状的实际患病率及相关危险因素。为研究俄罗斯非临床人群中抑郁症状的当前患病率，我们使用基于医院焦虑抑郁量表（HADS）抑郁分量表的在线调查进行了筛查。
该在线调查涵盖了2610名讲俄语的受访者，包括HADS抑郁分量表、关于性别、年龄以及受访者心血管疾病（CVD）诊断或症状的问题。
通过在线HADS抑郁分量表估计，有抑郁症状的受访者比例为14.4%（亚临床水平为11.5%，临床水平为2.9%）。女性（p = 0.003）、30岁以下的年轻人、42岁以上的参与者（p = 0.004）以及自我报告有CVD症状的个体（p = 0.00002）的HADS抑郁分量表总分更高。线性回归分析表明，自我报告的CVD症状会增加HADS抑郁分量表得分（p < 0.001），但男性（p = 0.002）和年龄较大（p < 0.001）会使其降低。逻辑回归表明，CVD症状会增加通过HADS抑郁分量表诊断出抑郁症状的风险（p = 0.033，OR = 1.29），但年龄较大（p = 0.015，OR = 0.87）和男性（呈趋势，p = 0.052，OR = 0.80）会降低这种风险。
基于HADS抑郁分量表的在线调查显示了俄罗斯非临床人群中抑郁症状患病率的新情况。抑郁症状患病率在男性和女性之间没有差异，且在年轻人中更高。抑郁症状与CVD之间的报告关联得到了证实。
