中药中天然药物提取物的抗诱变活性

Antimutagenicity of extracts from crude drugs in Chinese medicines.

作者信息

Sakai Y, Nagase H, Ose Y, Sato T, Yamada A, Hibi M, Yamada F

出版信息

Mutat Res. 1986 May;174(1):1-4. doi: 10.1016/0165-7992(86)90068-0.

Abstract

The antimutagenicity of extracts from crude drugs was studied by the Ames bioassay system. The crude drugs chosen were medical plants used very frequently as Chinese medicines. Each crude drug was extracted with hot water similar to the method of Chinese medical treatment. Antimutagenicity of the extract was found with 4 kinds of crude drugs, Paeoniae radix, Bupleuri radix, Hoelen and Glycyrrhizae radix. Each extract of the crude drug showed a different type of antimutagenic action from the others.

摘要

采用艾姆斯生物测定系统研究了生药提取物的抗诱变性。所选用的生药是非常常用的中药材。每种生药均采用类似于中医疗法的方法用热水提取。发现芍药根、柴胡根、茯苓和甘草根这4种生药的提取物具有抗诱变性。每种生药提取物表现出与其他提取物不同类型的抗诱变作用。