Smith P A, Johansson D, Tzannatos C, Campbell S
Prenat Diagn. 1986 Mar-Apr;6(2):133-41. doi: 10.1002/pd.1970060209.
The fetal cerebellum can be visualized with ultrasound throughout the second trimester. We describe a technique for measuring the transverse and anteroposterior cerebellar diameters and the measurement of the cisterna magna in the same plane between 14 and 32 weeks gestation. Nomograms for these measurements against gestational age showed good correlation, and narrow confidence limits for the transverse cerebellar diameter. The transverse cerebellar diameter was also measured directly in 79 fetuses after midtrimester abortion and the measurements obtained were compared with the ultrasound TCD nomogram. Good correlation, was obtained between the post mortem measurements and the ultrasound TCD nomogram. Routine use of these measurements and nomograms should prove valuable in the diagnosis of congenital abnormality of the posterior fossa and may also be of use in assessing the effect of severe intrauterine growth retardation and other insults on cerebellar growth and development. The narrow confidence limits obtained with the TCD nomogram should enable it to be used with confidence in clinical practice.
在整个孕中期，胎儿小脑可通过超声显像。我们描述了一种在妊娠14至32周时，在同一平面测量小脑横径和前后径以及测量小脑延髓池的技术。这些测量值与孕周的列线图显示出良好的相关性，且小脑横径的置信区间较窄。在孕中期流产后的79例胎儿中还直接测量了小脑横径，并将获得的测量值与超声小脑横径列线图进行比较。尸检测量值与超声小脑横径列线图之间获得了良好的相关性。常规使用这些测量值和列线图在诊断后颅窝先天性异常方面应具有重要价值，也可能有助于评估严重宫内生长受限和其他损伤对小脑生长发育的影响。小脑横径列线图获得的狭窄置信区间应使其能够在临床实践中放心使用。
