Liu Li, Yang Jingyuan, Wang Junhua, Nie Meng, Wang Ziyun, Guan Han, Hu Jin, Hong Feng
School of Public Health, The Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, Guizhou, People's Republic of China.
School of Public Health, Guizhou Medical University, Guiyang, Guizhou, People's Republic of China.
Neuropsychiatr Dis Treat. 2022 Feb 11;18:243-252. doi: 10.2147/NDT.S340834. eCollection 2022.
With over 2 million new cases annually, stroke is associated with the higher amount of disability-adjusted life-years lost than any other disease in China; however, the relationship between sleep time and stroke has not been concluded yet. Aim of this study was to analyze the relationship between sleep duration and stroke history in middle-aged and elderly people in Guiyang, China.
This study was a cross-sectional survey carried out in 40-99-years-old permanent residents of Guiyang. Yunyan, Wudang, and Baiyun districts and Xiuwen County were selected by stratified multilevel sampling for a face-to-face survey. Demographics, history of stroke, and self-reported sleep behavior data were collected, and multivariable logistic regression models were used to gradually adjust possible confounding factors.
A total of 5065 participants were included, of them 126 (2.5%) had a history of stroke. Short sleep (<7 h) was observed in 11.0%, sufficient sleep (7-9 h) in 69.4%, and long sleep (>9 h) in 19.6%. Sleep duration and stroke prevalence showed a U-shaped distribution. When taking the sleep duration of 7-9 h as a reference, sleep duration >9 h was associated with stroke (all P < 0.05) in the univariable model (OR = 2.68, 95% CI: 1.83-3.93) and in the multivariable models 1 (OR = 2.35, 95% CI: 1.59-3.47), 2 (OR = 2.27, 95% CI: 1.53-3.37), 3 (OR = 2.25, 95% CI: 1.51-3.33), and 4 (OR = 2.11, 95% CI: 1.39-3.19). There were no significant differences between the <7 and 7-9 h groups (P > 0.05).
Thus, long sleep duration (>9 h) is independently associated with history of stroke in middle-aged and elderly people in Guiyang.
在中国，中风每年新增病例超过200万，与其他任何疾病相比，中风导致的残疾调整生命年损失量更高；然而，睡眠时间与中风之间的关系尚未定论。本研究的目的是分析中国贵阳中老年人的睡眠时间与中风病史之间的关系。
本研究是一项针对贵阳市40至99岁常住居民的横断面调查。通过分层多级抽样选择云岩区、乌当区、白云区和修文县进行面对面调查。收集人口统计学信息、中风病史和自我报告的睡眠行为数据，并使用多变量逻辑回归模型逐步调整可能的混杂因素。
共纳入5065名参与者，其中126人（2.5%）有中风病史。观察到短睡眠（<7小时）者占11.0%，充足睡眠（7至9小时）者占69.4%，长睡眠（>9小时）者占19.6%。睡眠时间与中风患病率呈U形分布。以7至9小时的睡眠时间为参照，在单变量模型（OR = 2.68，95% CI：1.83至3.93）以及多变量模型1（OR = 2.35，95% CI：1.59至3.47）、模型2（OR = 2.27，95% CI：1.53至3.37）、模型3（OR = 2.25，95% CI：1.51至3.33）和模型4（OR = 2.11，95% CI：1.39至3.19）中，睡眠时间>9小时与中风相关（所有P < 0.05）。<7小时组与7至9小时组之间无显著差异（P > 0.05）。
因此，在贵阳的中老年人中，长睡眠时间（>9小时）与中风病史独立相关。
