Vaalasti A, Tainio H, Pelto-Huikko M, Hervonen A
Anat Rec. 1986 May;215(1):21-7. doi: 10.1002/ar.1092150104.
Vasoactive intestinal polypeptide (VIP) and enkephalins were demonstrated in the nerves of the human male urogenital tract by light and electron microscope immunohistochemical techniques. Nerves containing immunoreactivity to VIP were more numerous than enkephalin-immunoreactive nerves. Both VIP- and enkephalin-immunoreactive nerves were detected in the vas deferens, prostate, seminal vesicles, and urinary bladder. In the kidney, testis, and epididymis no immunoreactive nerves could be demonstrated. By electron microscope both types of immunoreactivities were localized to the large granular vesicles of nerve terminals. VIP-immunoreactive nerves were mostly found subepithelially, whereas enkephalin-immunoreactive nerves were mainly related to smooth muscle cells. The possible functions of these peptide-containing nerves are discussed.
采用光镜和电镜免疫组织化学技术，在人类男性泌尿生殖道的神经中证实了血管活性肠肽（VIP）和脑啡肽的存在。含有VIP免疫反应性的神经比脑啡肽免疫反应性神经数量更多。在输精管、前列腺、精囊和膀胱中均检测到了VIP和脑啡肽免疫反应性神经。在肾脏、睾丸和附睾中未发现免疫反应性神经。通过电镜观察，两种免疫反应性均定位于神经末梢的大颗粒囊泡。VIP免疫反应性神经大多位于上皮下，而脑啡肽免疫反应性神经主要与平滑肌细胞相关。本文讨论了这些含肽神经的可能功能。
