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异位肾患者的局部进展期直肠癌:病例报告及文献综述

Locally advanced rectal cancer in a patient with ectopic kidney: case report and literature review.

作者信息

Alsaawy Saad Mohammed

机构信息

Department of Surgery, College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj 16278, Saudi Arabia.

出版信息

J Surg Case Rep. 2022 Feb 16;2022(2):rjac024. doi: 10.1093/jscr/rjac024. eCollection 2022 Feb.

Abstract

The coexistence of ectopic kidney with locally advanced rectal cancer is rare. It poses a surgical and oncological challenge for the treating team. Careful preoperative surgical planning and decision about the neoadjuvant treatment are paramount.We report a 40-year-old male newly diagnosed with rectal adenocarcinoma with ectopic kidney. His preoperative staging was T3N2M0 with ectopic malrotated left kidney. After discussion in the multi-disciplinary team meeting, decision was to omit the neoadjuvant treatment and to go for low anterior resection. The procedure started open, and the findings showed the kidney lying in retroperitoneum around 3 cm above the peritoneal reflection and was separable from the tumor. Oncological resection of the rectosigmoid colon by lateral to medial approach with separation and preservation of the kidney, an end-to-end stapler anastomosis followed with a protective loop ileostomy. The patient had a smooth postoperative course, and the final pathology was T3N1Mx. He received eight cycles of adjuvant XELOX and was free of diseases on 1 year follow-up. There is no optimal option in managing this scenario due to a highly variable blood supply of the ectopic kidney and rarity of this condition. Multi-disciplinary team meeting with preoperative radiological mapping and patient counseling is crucial in making the best decision.

摘要

异位肾与局部进展期直肠癌并存的情况罕见。这给治疗团队带来了手术和肿瘤学方面的挑战。术前仔细的手术规划以及关于新辅助治疗的决策至关重要。我们报告一例40岁男性新诊断为伴有异位肾的直肠腺癌。他的术前分期为T3N2M0,伴有异位旋转不良的左肾。在多学科团队会议讨论后,决定省略新辅助治疗,进行低位前切除术。手术开始时采用开放手术,术中发现肾脏位于腹膜反折上方约3厘米处的腹膜后,可与肿瘤分离。通过从外侧向内侧的方法对直肠乙状结肠进行肿瘤切除,分离并保留肾脏,随后进行端端吻合器吻合,并做保护性回肠造口术。患者术后恢复顺利,最终病理结果为T3N1Mx。他接受了8个周期的辅助性XELOX治疗,在1年的随访中无疾病复发。由于异位肾的血供高度可变且这种情况罕见,在处理这种情况时没有最佳选择。术前进行放射学定位和患者咨询的多学科团队会议对于做出最佳决策至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb8e/8849412/4d5a008e2197/rjac024f1.jpg

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