Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China.
Centre for Public Health, Queen's University Belfast, United Kingdom.
Diabetes Res Clin Pract. 2022 Mar;185:109785. doi: 10.1016/j.diabres.2022.109785. Epub 2022 Feb 18.
We aimed to conduct a systematic review of published studies on the incidence of type 2 diabetes in children and adolescents aged under 20 years and provide worldwide incidence estimates for 2021.
We used MEDLINE and EMBASE to identify studies reporting type 2 diabetes incidence in children and adolescents published between Jan 2000 and April 2021. We used a negative binomial regression model to develop a prediction equation to estimate incidence rates from country characteristics. We applied the resulting incidence predictions to country population data to estimate numbers of incident cases in children and adolescents by International Diabetes Federation (IDF) region and World Bank income classification group.
We estimate that there are approximately 41,600 new cases of diagnosed type 2 diabetes among children and adolescents in 2021 worldwide. Around 30% and 40% of the worldwide total incident cases are in IDF Western Pacific region and in World Bank upper-middle-income countries, respectively. The three countries with the highest estimated number of incident cases are China, India, and United States of America.
The number of newly diagnosed type 2 diabetes in children and adolescents is substantial. More reliable data are needed to track the incidence of type 2 diabetes in children and adolescents.
我们旨在对已发表的关于 20 岁以下儿童和青少年 2 型糖尿病发病率的研究进行系统综述，并提供 2021 年的全球发病率估计值。
我们使用 MEDLINE 和 EMBASE 检索了 2000 年 1 月至 2021 年 4 月期间发表的关于儿童和青少年 2 型糖尿病发病率的研究报告。我们使用负二项回归模型建立了一个预测方程，以根据国家特征估计发病率。我们将由此产生的发病率预测应用于国家人口数据，以按国际糖尿病联合会（IDF）区域和世界银行收入分类组估计儿童和青少年的新发病例数。
我们估计，2021 年全球约有 41600 例新诊断的儿童和青少年 2 型糖尿病病例。全球总发病例的约 30%和 40%分别在 IDF 西太平洋地区和世界银行中上收入国家。预计发病例数最高的三个国家是中国、印度和美国。
新诊断的儿童和青少年 2 型糖尿病病例数量相当可观。需要更可靠的数据来跟踪儿童和青少年 2 型糖尿病的发病率。
