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局限性硬皮病(硬斑病)中表皮萎缩的评估。

Assessment of epidermal atrophy in localized scleroderma (morphea).

作者信息

Serup J

出版信息

Dermatologica. 1986;172(4):205-8. doi: 10.1159/000249336.

Abstract

The skin surface of scleroderma skin becomes glossy as a result of epidermal atrophy. In this study, the skin relief was studied in 12 patients with localized scleroderma (morphea). Measurements by a stylus method showed smoothening of the skin in all plaques studied (p less than 0.01). Ultrasound measurement showed increased skin thickness (p less than 0.01). There was no correlation between smoothening of the skin surface and increase in skin thickness, and no correlation to the duration of the plaques. It is concluded that glossy appearance of plaques of scleroderma is an early sign, which may be useful in the clinical diagnosis of scleroderma.

摘要

由于表皮萎缩,硬皮病皮肤的表面变得光滑。在本研究中,对12例局限性硬皮病(硬斑病)患者的皮肤起伏进行了研究。用触针法测量显示,所有研究斑块的皮肤均变平滑(p<0.01)。超声测量显示皮肤厚度增加(p<0.01)。皮肤表面平滑与皮肤厚度增加之间无相关性,与斑块持续时间也无相关性。结论是,硬皮病斑块的光滑外观是一个早期体征,可能有助于硬皮病的临床诊断。

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