Suppr超能文献

肥胖还是健康对于老年智障人士的生存更关键?

Is fatness or fitness key for survival in older adults with intellectual disabilities?

机构信息

Department of General Practice, Intellectual Disability Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Department of Kinesiology and Nutrition, University of Illinois, Chicago, Illinois.

出版信息

J Appl Res Intellect Disabil. 2020 Sep;33(5):1016-1025. doi: 10.1111/jar.12724. Epub 2020 Mar 13.

Abstract

BACKGROUND

Overweight/obesity and poor physical fitness are two prevalent lifestyle-related problems in older adults with intellectual disabilities, which each require a different approach. To improve healthy ageing, we assessed whether fatness or fitness is more important for survival in older adults with intellectual disabilities.

METHODS

In the HA-ID study, we measured obesity and fitness of 874 older adults with intellectual disabilities (61.4 ± 7.8 years). All-cause mortality was assessed over a 5-year follow-up period.

RESULTS

Fitness, but not obesity, was significantly related to survival (HR range of 0.17-0.22). People who were unfit were 3.58 (95% CI = 1.72-7.46) to 4.59 (95% CI = 1.97-10.68) times more likely to die within the follow-up period than people who were fit, regardless of obesity.

CONCLUSION

This was the first study to show that being fit is more important for survival than fatness in older adults with intellectual disabilities. The emphasis should, therefore, shift from weight reduction to improving physical fitness.

摘要

背景

超重/肥胖和身体状况不佳是智力障碍老年人中两种普遍存在的与生活方式相关的问题,两者都需要采取不同的方法。为了促进健康老龄化,我们评估了在智力障碍老年人中,肥胖和健康状况对生存的重要性。

方法

在 HA-ID 研究中,我们测量了 874 名智力障碍老年人(61.4±7.8 岁)的肥胖和健康状况。在 5 年的随访期间评估全因死亡率。

结果

健康状况,但不是肥胖,与生存显著相关(HR 范围为 0.17-0.22)。无论肥胖与否,不适合的人在随访期间死亡的可能性是健康的人的 3.58(95%CI=1.72-7.46)至 4.59(95%CI=1.97-10.68)倍。

结论

这是第一项表明在智力障碍老年人中,健康状况比肥胖对生存更重要的研究。因此,重点应该从减肥转移到提高身体的健康状况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb34/7496297/79be4014ada0/JAR-33-1016-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验