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Heterogeneity of desmin, the muscle-type intermediate filament protein, in blood vessels and astrocytes.

作者信息

Dahl D, Zapatka S, Bignami A

出版信息

Histochemistry. 1986;84(2):145-50. doi: 10.1007/BF00499825.

DOI:10.1007/BF00499825
PMID:3519540
Abstract

Monoclonal antibodies were isolated from mice immunized with chicken gizzard desmin. Antibodies reacting with desmin on immunoblots and selectively decorating chicken and rat intestinal smooth muscle as well as the Z-line in striated muscle, were selected for this study. Based on their staining pattern on cryostat sections of chicken and rat cerebellum, spleen, kidney, aorta and femoral artery, monoclonal supernatants could be divided in three groups: (i) antibodies decorating astrocytes and vascular smooth muscle; (ii) antibodies decorating only vascular smooth muscle; (iii) antibodies decorating only astrocytes. Antibodies in group (i) and (iii) also stained GFA-negative Bergmann glia in chicken cerebellum. It is proposed that desmin may vary depending on the histological localization.

摘要

相似文献

1
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2
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本文引用的文献

1
Antibodies to neurofilament, glial filament, and fibroblast intermediate filament proteins bind to different cell types of the nervous system.针对神经丝、胶质丝和成纤维细胞中间丝蛋白的抗体与神经系统的不同细胞类型结合。
J Cell Biol. 1981 Jan;88(1):115-26. doi: 10.1083/jcb.88.1.115.
2
Heterogeneity of intermediate filament expression in vascular smooth muscle: a gradient in desmin positive cells from the rat aortic arch to the level of the arteria iliaca communis.血管平滑肌中间丝表达的异质性：从大鼠主动脉弓到髂总动脉水平，结蛋白阳性细胞呈梯度变化。
Differentiation. 1981;20(3):196-202. doi: 10.1111/j.1432-0436.1981.tb01176.x.
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不同表达胶质纤维酸性蛋白的小鼠胶质瘤克隆皮下肿瘤中的胶质细丝。一项免疫组织化学和超微结构研究。
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4
Intermediate filament proteins immunologically related to desmin in astrocytes: a study of chicken spinal cord by two-dimensional gel electrophoresis and immunoblotting.星形胶质细胞中与结蛋白免疫相关的中间丝蛋白：二维凝胶电泳和免疫印迹法对鸡脊髓的研究
Neurochem Res. 1989 Oct;14(10):1013-6. doi: 10.1007/BF00965936.
5
The developing neuroepithelium in human embryonic and fetal brain studied with vimentin-immunocytochemistry.用波形蛋白免疫细胞化学法研究人类胚胎和胎儿大脑中正在发育的神经上皮。
Anat Embryol (Berl). 1989;180(1):17-28. doi: 10.1007/BF00321896.
6
Unexpected immunoreactivities of intermediate filament antibodies in human brain and brain tumors.人脑中及脑肿瘤中中间丝抗体的意外免疫反应性。
Am J Pathol. 1991 Jul;139(1):67-79.
Immunohistological localization of desmin, the muscle-type 100 A filament protein, in rat astrocytes and Müller glia.
结蛋白（一种肌型100 A细丝蛋白）在大鼠星形胶质细胞和米勒胶质细胞中的免疫组织学定位。
J Histochem Cytochem. 1982 Mar;30(3):207-13. doi: 10.1177/30.3.7037941.
4
Distribution of vimentin and desmin filaments in smooth muscle tissue of mammalian and avian aorta.波形蛋白和结蛋白丝在哺乳动物及鸟类主动脉平滑肌组织中的分布。
Exp Cell Res. 1982 Feb;137(2):329-40. doi: 10.1016/0014-4827(82)90034-9.
5
Filament proteins in rat optic nerves undergoing Wallerian degeneration: localization of vimentin, the fibroblastic 100-A filament protein, in normal and reactive astrocytes.发生华勒氏变性的大鼠视神经中的细丝蛋白：波形蛋白（成纤维细胞的100埃细丝蛋白）在正常和反应性星形胶质细胞中的定位。
Exp Neurol. 1981 Aug;73(2):496-506. doi: 10.1016/0014-4886(81)90283-1.
6
Aortic smooth muscle cells contain vimentin instead of desmin.主动脉平滑肌细胞含有波形蛋白而非结蛋白。
Proc Natl Acad Sci U S A. 1981 May;78(5):3020-4. doi: 10.1073/pnas.78.5.3020.
7
Vascular smooth muscle cells differ from other smooth muscle cells: predominance of vimentin filaments and a specific alpha-type actin.血管平滑肌细胞与其他平滑肌细胞不同：波形蛋白丝占优势且有特定的α型肌动蛋白。
Proc Natl Acad Sci U S A. 1981 Jan;78(1):298-302. doi: 10.1073/pnas.78.1.298.
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Glial cells in the enteric nervous system contain glial fibrillary acidic protein.肠神经系统中的神经胶质细胞含有胶质纤维酸性蛋白。
Nature. 1980 Aug 14;286(5774):736-7. doi: 10.1038/286736a0.
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Co-existence of vimentin and desmin type intermediate filaments in a subpopulation of adult rat vascular smooth muscle cells growing in primary culture.在原代培养中生长的成年大鼠血管平滑肌细胞亚群中波形蛋白和结蛋白类型中间丝的共存。
Exp Cell Res. 1982 May;139(1):87-94. doi: 10.1016/0014-4827(82)90321-4.
10
Molecular identity, distribution and heterogeneity of glial fibrillary acidic protein: an immunoblotting and immunohistochemical study of Schwann cells, satellite cells, enteric glia and astrocytes.胶质纤维酸性蛋白的分子特性、分布及异质性：施万细胞、卫星细胞、肠神经胶质细胞和星形胶质细胞的免疫印迹及免疫组织化学研究
J Neurocytol. 1984 Apr;13(2):187-200. doi: 10.1007/BF01148114.