Université de Lyon, Université Claude Bernard Lyon 1, Institut de Chimie et de Biochimie Moléculaires et Supramoléculaires, UMR 5246, CNRS, CPE, Villeurbanne, France.
Institut National Des Sciences Appliquées, INSA Lyon, Villeurbanne, France.
Astrobiology. 2022 May;22(5):598-627. doi: 10.1089/ast.2021.0059. Epub 2022 Feb 23.
Phospholipids are essential components of biological membranes and are involved in cell signalization, in several enzymatic reactions, and in energy metabolism. In addition, phospholipids represent an evolutionary and non-negligible step in life emergence. Progress in the past decades has led to a deeper understanding of these unique hydrophobic molecules and their most pertinent functions in cell biology. Today, a growing interest in "prebiotic lipidomics" calls for a new assessment of these relevant biomolecules.
磷脂是生物膜的重要组成部分，参与细胞信号转导、多种酶反应和能量代谢。此外，磷脂在生命起源过程中是一个具有进化意义且不可忽视的步骤。过去几十年的研究进展使人们对这些独特的疏水分子及其在细胞生物学中的重要功能有了更深入的了解。如今，“前生物脂质组学”的兴起要求对这些相关生物分子进行新的评估。
