Simpson Cassandra, Mittal Rea, Jain Rahul, Jain Rohit
Lake Erie College of Osteopathic Medicine, Erie, PA 21502, USA.
Penn State College of Medicine, Hershey, PA 17033, USA.
Future Cardiol. 2022 Apr;18(4):337-343. doi: 10.2217/fca-2021-0045. Epub 2022 Feb 24.
Peripartum cardiomyopathy (PPCM) is systolic heart failure in a woman who is pregnant or in the early postpartum period. There are multiple theories regarding the pathophysiology of this disease, and it is suspected the true cause is a combination of these theories. Presenting symptoms are similar to that of systolic heart failure from other causes and must be carefully differentiated from normal changes that occur during pregnancy. PPCM may progress to chronic heart failure and result in various complications if not treated early. This paper offers a comprehensive review of currently accepted pathophysiologic theories, major signs and symptoms, possible complications and treatments of PPCM.
围产期心肌病(PPCM)是指妊娠期间或产后早期女性发生的收缩性心力衰竭。关于这种疾病的病理生理学有多种理论,人们怀疑其真正病因是这些理论的综合作用。其表现症状与其他原因引起的收缩性心力衰竭相似,必须与妊娠期间发生的正常变化仔细区分。如果不及早治疗,PPCM可能会进展为慢性心力衰竭并导致各种并发症。本文全面综述了目前公认的PPCM病理生理学理论、主要体征和症状、可能的并发症及治疗方法。