The State Key Laboratory of Refractories and Metallurgy, School of Chemistry & Chemical Engineering, Wuhan University of Science and Technology, Wuhan 430081, P. R. China.
Anticancer Agents Med Chem. 2022;22(13):2354-2357. doi: 10.2174/1871520622666220222141609.
The growth of nanotechnology has revolutionized the diagnosis and treatment of diseases with high precision and effectiveness. Nanoparticles (NPs) represent a major point of attention in the scientific field, with an increasing number of studies revealing promising results. The unique physicochemical properties, biocompatibility, and highly developed chemical properties of gold nanoparticles (AuNPs) have promoted breakthroughs in the cancer community, focusing on the therapeutic and diagnostic applications of cancer diagnosis and treatment. This perspective aims to summarize the latest research on multifunctional AuNPs as therapeutic, diagnostic agents in cancer diagnosis and treatment. Several nanostructured hybrid AuNPs have been reviewed, and their applications in imaging, targeting, therapy, and delivery have been discussed.
纳米技术的发展已经彻底改变了疾病的诊断和治疗方式，具有高精度和高效性。纳米粒子（NPs）是科学界关注的一个主要焦点，越来越多的研究揭示了其有前景的结果。金纳米粒子（AuNPs）具有独特的物理化学性质、生物相容性和高度发达的化学性质，推动了癌症领域的突破，专注于癌症诊断和治疗的治疗和诊断应用。本观点旨在总结多功能 AuNPs 作为癌症诊断和治疗的治疗、诊断剂的最新研究。综述了几种纳米结构杂化 AuNPs，并讨论了它们在成像、靶向、治疗和递送上的应用。
