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工程化配体金纳米团簇作为癌症应用的高效治疗诊断一体化试剂。

Engineering Liganded Gold Nanoclusters as Efficient Theranostic Agents for Cancer Applications.

机构信息

Center of Excellence for Science and Technology-Integration of Mediterranean Region (STIM) at, Interdisciplinary Center for Advanced Sciences and Technology (ICAST), University of Split, Poljička cesta 35, 21000, Split, Croatia.

Chemistry Department, Humboldt University of Berlin, Brook-Taylor-Strasse 2, 12489, Berlin, Germany.

出版信息

Chembiochem. 2023 Feb 14;24(4):e202200524. doi: 10.1002/cbic.202200524. Epub 2022 Nov 16.

Abstract

Luminescent gold nanoclusters are rapidly gaining attention as efficient theranostic targets for imaging and therapeutics. Indeed, their ease of synthesis, their tunable optical properties and tumor targeting make them potential candidates for sensitive diagnosis and efficacious therapeutic applications. This concept highlights the key components for designing gold nanoclusters as efficient theranostics focusing on application in the field of oncology.

摘要

发光金纳米团簇作为一种高效的成像和治疗两用的治疗靶点,正受到越来越多的关注。事实上,它们易于合成、可调谐的光学性质和肿瘤靶向性使它们成为用于敏感诊断和有效治疗应用的潜在候选物。这一概念强调了设计作为高效治疗剂的金纳米团簇的关键组成部分,重点是在肿瘤学领域的应用。

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