Nigatu Balkachew, Workneh Tigist, Mekuria Thomas, Yifter Helen, Mamuye Yeshiwondim, Gize Addisu
Department of Obstetrics and Gynecology, St. Paul Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Department of Internal Medicine, St. Paul Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Clin Diabetes Endocrinol. 2022 Feb 23;8(1):2. doi: 10.1186/s40842-022-00139-w.
The prevalence of Gestational Diabetes Mellitus (GDM) varies worldwide among racial and ethnic groups, population characteristics (eg, average age and body mass index (BMI) of pregnant women), testing method, and diagnostic criteria. This study was aimed at determining the prevalence of GDM using the one-step 75-g Oral glucose tolerance test (OGTT) protocol, with plasma glucose measurement taken when patient is fasting and at 1 and 2 h and identify associated risk factors among pregnant women attending antenatal care clinic at St. Paul Hospital Millennium Medical College (SPHMMC) in Addis Ababa, Ethiopia.
Institution based cross sectional study was conducted from April, 2017 to October, 2017 at antenatal care clinic of SPHMMC among a randomly selected sample of 390 eligible pregnant women. Data were collected using a pretested questioner using 5% of the total sample size and later was modified accordingly to capture all the necessary data. Descriptive statistics, independent t-test and Binary Logistic Regression were used for analysis using SPSS version 23.0.
The prevalence of GDM among the study population was 16.9%. Factors that affect prevalence of GDM were age group (AOR = 2.75, 95% CI: 1.03, 7.35 for 30-34 years old and AOR = 4.98, 95% CI: 1.703, 14.578 for ≥ 35 years old)and BMI (AOR = 2.23, 95% CI: 1.21, 4.11).
The prevalence of GDM among the study population is higher than previous reports in Ethiopia and even in other countries. This implies that these women and their newborns might be exposed to increased risk of immediate and long term complications from GDM including future risk of GDM and Type II Diabetes Mellitus.
妊娠期糖尿病(GDM)在全球不同种族和族裔群体、人群特征(如孕妇平均年龄和体重指数(BMI))、检测方法及诊断标准之间的患病率存在差异。本研究旨在采用一步法75克口服葡萄糖耐量试验(OGTT)方案,在患者空腹、1小时和2小时时测量血糖,以确定埃塞俄比亚亚的斯亚贝巴圣保罗医院千禧医学院(SPHMMC)产前护理诊所就诊的孕妇中GDM的患病率,并识别相关危险因素。
2017年4月至2017年10月,在SPHMMC的产前护理诊所对390名随机抽取的符合条件的孕妇进行了基于机构的横断面研究。使用预先测试的问卷收集数据,问卷最初基于总样本量的5%进行设计,随后进行了相应修改以获取所有必要数据。使用SPSS 23.0软件进行描述性统计、独立t检验和二元逻辑回归分析。
研究人群中GDM的患病率为16.9%。影响GDM患病率的因素包括年龄组(30 - 34岁组的调整后比值比(AOR)= 2.75,95%置信区间(CI):1.03,7.35;≥35岁组的AOR = 4.98,95% CI:1.703,14.578)和BMI(AOR = 2.23,95% CI:1.21,4.11)。
研究人群中GDM的患病率高于埃塞俄比亚此前的报告,甚至高于其他国家。这意味着这些妇女及其新生儿可能面临GDM导致的近期和长期并发症风险增加,包括未来患GDM和2型糖尿病的风险。