Webster Amanda, McNair Helen A, Hansen Vibeke N, Lewis Rebecca, Patel Emma, Miles Elizabeth, Hall Emma, Hafeez Shaista, Huddart Robert
National Radiotherapy Trials Quality Assurance Group (RTTQA), University College Hospital (UCLH), London, United Kingdom.
Division of Radiotherapy and Imaging, Institute of Cancer Research, London, United Kingdom.
Tech Innov Patient Support Radiat Oncol. 2022 Feb 9;21:31-35. doi: 10.1016/j.tipsro.2022.01.002. eCollection 2022 Mar.
Two multicentre adaptive radiotherapy trials utilising Plan of the Day (PoD) with a library of plans were introduced in 35 centres. The common issues that arose from all centres when introducing PoD were collated retrospectively, through reviewing the data pertaining to the pre-trial and on-trial quality assurance programme. It was found that 1,295 issues arose when introducing PoD in outlining, planning, treatment delivery i.e., PoD selection, and in the overall process of delivering PoD. There was no difference in the number of issues that arose from pre-trial to on-trial. Thus, it is recommended that the implementation of PoD is supported by guidance, reviews, and continuous monitoring.
两项利用当日计划(PoD)和计划库的多中心适应性放射治疗试验在35个中心开展。通过回顾与试验前和试验期间质量保证计划相关的数据,对所有中心在引入PoD时出现的常见问题进行了回顾性整理。结果发现,在引入PoD的轮廓勾画、计划制定、治疗实施(即PoD选择)以及PoD交付的整个过程中出现了1295个问题。试验前到试验期间出现的问题数量没有差异。因此,建议通过指导、审查和持续监测来支持PoD的实施。