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Do liberal thresholds for red cell transfusion result in improved quality of life for patients undergoing intensive chemotherapy for acute myeloid leukemia? A randomized crossover feasibility study.

作者信息

Morton Suzy, Sekhar Mallika, Smethurst Heather, Mora Ana, Hodge Renate L, Hudson Cara L, Parsons Joseph, Hopkins Valerie, Stanworth Simon J

机构信息

Department of Clinical Haematology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom. B15 2WB; Medical Department, NHS Blood and Transplant, Birmingham, United Kingdom. B15 2SG.

Department of Haematology, University College London Hospitals NHS Foundation Trust, London, United Kingdom. NW1 2BU; Royal Free London NHS Foundation Trust, Department of Haematology, London, United Kingdom. NW3 2QG.

出版信息

Haematologica. 2022 Jun 1;107(6):1474-1478. doi: 10.3324/haematol.2021.279867.

DOI:10.3324/haematol.2021.279867
PMID:35199504
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9152957/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f21d/9152957/49d6a474ed9a/1071474.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f21d/9152957/49d6a474ed9a/1071474.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f21d/9152957/49d6a474ed9a/1071474.fig1.jpg

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本文引用的文献

1
Supportive care in the management of patients with acute myeloid leukaemia: where are the research needs?
Br J Haematol. 2020 Aug;190(3):311-313. doi: 10.1111/bjh.16708. Epub 2020 May 7.
2
Liberal Versus Restrictive Red Blood Cell Transfusion Thresholds in Hematopoietic Cell Transplantation: A Randomized, Open Label, Phase III, Noninferiority Trial.造血干细胞移植中自由与限制红细胞输血阈值的比较:一项随机、开放标签、III 期、非劣效性试验。
J Clin Oncol. 2020 May 1;38(13):1463-1473. doi: 10.1200/JCO.19.01836. Epub 2020 Feb 21.
3
Red cell transfusion in outpatients with myelodysplastic syndromes: a feasibility and exploratory randomised trial.骨髓增生异常综合征门诊患者的红细胞输注:一项可行性和探索性随机试验。
输血阈值:在需要长期输血治疗的血液系统疾病中采用以患者为中心方法的必要性。
Blood Res. 2023 Apr 30;58(S1):S8-S10. doi: 10.5045/br.2023.2023009. Epub 2023 Feb 27.
Br J Haematol. 2020 Apr;189(2):279-290. doi: 10.1111/bjh.16347. Epub 2020 Jan 20.
4
Valuing health-related quality of life: An EQ-5D-5L value set for England.重视与健康相关的生活质量:英国的EQ-5D-5L价值集。
Health Econ. 2018 Jan;27(1):7-22. doi: 10.1002/hec.3564. Epub 2017 Aug 22.
5
Clinical Practice Guidelines From the AABB: Red Blood Cell Transfusion Thresholds and Storage.美国血库协会临床实践指南:红细胞输注阈值与储存
JAMA. 2016 Nov 15;316(19):2025-2035. doi: 10.1001/jama.2016.9185.
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