Department of Pulmonary, Critical Care and Sleep Medicine, B. P. Koirala Institute of Health Sciences, Dharan, Nepal.
Department of Paediatrics and Adolescent Medicine, B. P. Koirala Institute of Health Sciences, Dharan, Nepal.
JNMA J Nepal Med Assoc. 2021 Nov 15;59(243):1170-1173. doi: 10.31729/jnma.6841.
Non-bacterial thrombotic endocarditis is a rare condition characterized by noninfectious vegetation on cardiac valves which are often associated with malignancy. It often presents with features of embolism rather than cardiac failure. These are usually seen in autoimmune conditions, disseminated intravascular coagulation, malignancy of gut and lung but has also been reported in other malignancies as well. This entity is rare but one must have a clinical suspicion of the disease especially in a patient suffering from malignancy presenting with the embolic phenomenon. In this report, we are presenting a case of non-bacterial thrombotic endocarditis in an inpatient with pleural mesothelioma, a rare malignant neoplasm arising from pleura in a 35 years old mason, and a rare association as well.
非细菌性血栓性心内膜炎是一种罕见的疾病,其特征是心脏瓣膜上存在非感染性的赘生物,通常与恶性肿瘤有关。它常表现为栓塞的特征,而不是心力衰竭。这些通常见于自身免疫性疾病、弥散性血管内凝血、胃肠道和肺部恶性肿瘤,但也有其他恶性肿瘤的报道。这种疾病虽然罕见,但对于患有恶性肿瘤并出现栓塞现象的患者,临床医生必须高度怀疑该病的存在。在本报告中,我们介绍了一例胸膜间皮瘤住院患者的非细菌性血栓性心内膜炎病例,这是一种罕见的恶性肿瘤,发生于一名 35 岁的泥瓦匠的胸膜上,也是一种罕见的关联。