Alhendi Aseel, Khounganian Rita, Almudhi Abdullazez, Ahamad Syed Rizwan
Department of Pediatric Dentistry and Orthodontics, College of Dentistry, King Saud University, P.O. Box 60169, Riyadh 11545, Saudi Arabia.
Department of Oral Medicine and Diagnostic Sciences, College of Dentistry, King Saud University, Riyadh 11545, Saudi Arabia.
Dent J (Basel). 2022 Feb 14;10(2):27. doi: 10.3390/dj10020027.
The aim of this study was to investigate and compare the leaching of four different clear aligner systems (Invisalign, Eon, SureSmile, and Clarity). Three sets of aligners as obtained from the four manufacturers were cut and immersed in glass vials containing ethanol with different solutions. The first was 100% ethanol, the second was 75% ethanol to 25% water, the third was 50% ethanol to water, the fourth was 25% ethanol to 75% water, and the last was 100% water. The samples were incubated for two weeks at 37 °C. Leached substances were detected by the gas chromatography-mass spectrometry (GC-MS). Eleven different chemical compounds were detected and confirmed. Benzene1,3-bis(1,1-dimethylethyl) was the only compound detected in all four systems at levels of 100% and 75% ethanol. Statistically, insignificant differences were detected among the different systems where leaching was confirmed. Eon system was the only material to show statistically significant differences when comparing the number of leached substances among the immersion solution concentrations. The four included systems showed variable degrees of leaching. The lowest amount of leached chemicals was observed in relation to the Invisalign system, while the highest number was found in the Eon system. None of the included clear aligner systems leached detectable amounts of bisphenol-A (BPA).
本研究的目的是调查和比较四种不同的透明矫治器系统（隐适美、Eon、SureSmile和Clarity）的浸出情况。从四家制造商处获得的三组矫治器被切割并浸入装有不同溶液的玻璃瓶中。第一种是100%乙醇，第二种是75%乙醇与25%水，第三种是50%乙醇与水，第四种是25%乙醇与75%水，最后一种是100%水。样品在37℃下孵育两周。通过气相色谱-质谱联用仪（GC-MS）检测浸出物质。检测并确认了11种不同的化合物。1,3-双（1,1-二甲基乙基）苯是在所有四个系统中在100%和75%乙醇水平下检测到的唯一化合物。在确认有浸出的不同系统之间，统计学上未检测到显著差异。在比较浸液浓度之间的浸出物质数量时，Eon系统是唯一显示出统计学显著差异的材料。所纳入的四个系统显示出不同程度的浸出。与隐适美系统相关的浸出化学物质数量最少，而Eon系统中浸出化学物质数量最多。所纳入的透明矫治器系统均未浸出可检测量的双酚A（BPA）。
