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用于放射治疗的含氯化钙的β-(羟甲基)丙烯酰胺凝胶剂量计的剂量响应改善

Improved Dose Response of -(hydroxymethyl)acrylamide Gel Dosimeter with Calcium Chloride for Radiotherapy.

作者信息

Rabaeh Khalid A, Al-Tarawneh Rawan E, Eyadeh Molham M, Hammoudeh Issra' M E, Shatnawi Moneeb T M

机构信息

Medical Imaging Department, Faculty of Applied Medical Sciences, The Hashemite University, Zarqa 13133, Jordan.

Physics Department, School of Science, The University of Jordan, Amman 11942, Jordan.

出版信息

Gels. 2022 Jan 26;8(2):78. doi: 10.3390/gels8020078.

Abstract

The impact of calcium chloride (CaCl) on the performance of -(hydroxymethyl)acrylamide (NHMA) polymer gel dosimeter is studied in this article. The dosimeter was exposed to doses of up to 10 Gy with radiation beam-energy of 10 MV and dose-rates of 300 cGy/min. The relaxation rate (R) parameter was utilized to explore the performance of irradiated NHMAGAT gels. The dose response in terms of R increased from 0.29 to 0.63 Gy·s with increasing calcium chloride concentration from 0 to 1000 mM. The results show no substantial impact of dose-rates as well as radiation energies on NHMAGAT samples. For the steadiness of irradiated NHMAGAT dosimeters, it was found that there is no apparent variation in R (less than ±3%; standard deviation) up to 3 days. The overall uncertainty of the gel dosimeter with calcium chloride is 4.96% (double standard deviation, 95% confidence level).

摘要

本文研究了氯化钙(CaCl)对β-(羟甲基)丙烯酰胺(NHMA)聚合物凝胶剂量计性能的影响。该剂量计在10 MV的辐射束能量和300 cGy/min的剂量率下接受高达10 Gy的剂量照射。利用弛豫率(R)参数来探究辐照后的NHMAGAT凝胶的性能。随着氯化钙浓度从0增加到1000 mM,R的剂量响应从0.29增加到0.63 Gy·s。结果表明,剂量率和辐射能量对NHMAGAT样品没有实质性影响。对于辐照后的NHMAGAT剂量计的稳定性,发现直到3天R没有明显变化(小于±3%;标准偏差)。含氯化钙的凝胶剂量计的总体不确定度为4.96%(双标准偏差,95%置信水平)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb92/8871509/8b7792485573/gels-08-00078-g001a.jpg

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