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术前葡萄糖-胰岛素-钾对心肌糖原水平及二尖瓣置换术并发症的影响。

Effects of preoperative glucose-insulin-potassium on myocardial glycogen levels and on complications of mitral valve replacement.

作者信息

Oldfield G S, Commerford P J, Opie L H

出版信息

J Thorac Cardiovasc Surg. 1986 Jun;91(6):874-8.

PMID:3520160
Abstract

Myocardial glycogen content was increased from a mean of 25.8 +/- 3.7 to 40.3 +/- 4.2 mumol/gm (p less than 0.0001) by an infusion of glucose, insulin, and potassium before mitral valve replacement. Patients who had received such an infusion and who had a higher myocardial glycogen content had a lower incidence of postoperative hypotension, less serious postoperative arrhythmias, and fewer serious complications after elective mitral valve replacement.

摘要

在二尖瓣置换术前,通过输注葡萄糖、胰岛素和钾,心肌糖原含量从平均25.8±3.7微摩尔/克增加到40.3±4.2微摩尔/克(p<0.0001)。接受这种输注且心肌糖原含量较高的患者,在择期二尖瓣置换术后发生术后低血压的发生率较低,术后心律失常较轻,严重并发症较少。

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