某菌属，作为……的近亲，在一名患有抗干扰素-γ（IFN-γ）自身抗体的患者中引发伴有胆汁淤积性肝炎的败血症。
sp., a Close Relative of , Causing Septicemia with Cholestatic Hepatitis in a Patient with Anti-Interferon-γ (IFN-γ) Autoantibodies.
作者信息
Kajeekul Rattagan, Insiripong Somchai, Riwlord Athita, Poomchuchit Suleeporn, Kerdsin Anusak
机构信息
Department of Medicine, Maharat Nakhon Ratchasima Hospital, Nakhon Ratchasima 30000, Thailand.
Clinical Microbiology Laboratory, Department of Medical Technology, Maharat Nakhon Ratchasima Hospital, Nakhon Ratchasima 30000, Thailand.
出版信息
Trop Med Infect Dis. 2022 Feb 11;7(2):25. doi: 10.3390/tropicalmed7020025.
is an intracellular, fastidious, Gram-negative bacterium that is difficult to identify using routine microbiological methods in the laboratory. We studied the isolation of sp. (strain IDAMR664) from the blood of a patient with anti-interferon-γ (IFN-γ) autoantibodies who presented with septicemia and cholestatic hepatitis. Analysis of the strain IDAMR664 genome sequence revealed the isolate was closely related to the strain GA01-2794 that had been isolated from a human in the USA. In addition, it was clustered with , a fish pathogen. The isolate contained several virulence factors and had pathogenicity island pattern no. 3.
是一种细胞内、苛求、革兰氏阴性菌，在实验室中使用常规微生物学方法难以鉴定。我们研究了从一名患有抗干扰素-γ（IFN-γ）自身抗体且出现败血症和胆汁淤积性肝炎的患者血液中分离出的 菌（菌株IDAMR664）。对菌株IDAMR664基因组序列的分析表明，该分离株与从美国一名人类身上分离出的GA01-2794菌株密切相关。此外，它与一种鱼类病原体 聚集在一起。该分离株含有多种毒力因子，且具有3号致病岛模式。
Zotero 插件