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应变成像用于原发性醛固酮增多症中心脏重塑和功能障碍的早期检测

Strain Imaging for the Early Detection of Cardiac Remodeling and Dysfunction in Primary Aldosteronism.

作者信息

Chen Yilin, Xu Tingyan, Xu Jianzhong, Zhu Limin, Wang Dian, Li Yan, Wang Jiguang

机构信息

Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.

State Key Laboratory of Medical Genomics, Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.

出版信息

Diagnostics (Basel). 2022 Feb 20;12(2):543. doi: 10.3390/diagnostics12020543.

DOI:10.3390/diagnostics12020543
PMID:35204632
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8871189/
Abstract

Speckle tracking echocardiography is a novel technique to quantify cardiac function and deformation. It has been applied in a series of cardiovascular diseases for the evaluation of early cardiac impairment. We recently used this technique to investigate cardiac structure and function in patients with primary aldosteronism. Cardiac damage usually occurs earlier in patients with primary aldosteronism than those with primary hypertension, probably because aldosterone hypersecretion is more commonly observed in the former than the latter patients. In this article, we will review the imaging studies, especially with speckle tracking echocardiography, for the detection of early cardiac dysfunction in primary aldosteronism as a disease model.

摘要

斑点追踪超声心动图是一种用于量化心脏功能和变形的新技术。它已被应用于一系列心血管疾病,用于评估早期心脏损害。我们最近使用该技术研究原发性醛固酮增多症患者的心脏结构和功能。原发性醛固酮增多症患者的心脏损害通常比原发性高血压患者出现得更早,这可能是因为前者比后者更常见醛固酮分泌过多。在本文中,我们将综述成像研究,特别是斑点追踪超声心动图,用于检测作为疾病模型的原发性醛固酮增多症中的早期心脏功能障碍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb5b/8871189/9995899387de/diagnostics-12-00543-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb5b/8871189/d88733415bac/diagnostics-12-00543-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb5b/8871189/c66001fb0a4c/diagnostics-12-00543-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb5b/8871189/d6c2d33b6a81/diagnostics-12-00543-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb5b/8871189/f5b92e72a5f6/diagnostics-12-00543-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb5b/8871189/9995899387de/diagnostics-12-00543-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb5b/8871189/d88733415bac/diagnostics-12-00543-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb5b/8871189/c66001fb0a4c/diagnostics-12-00543-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb5b/8871189/d6c2d33b6a81/diagnostics-12-00543-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb5b/8871189/f5b92e72a5f6/diagnostics-12-00543-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb5b/8871189/9995899387de/diagnostics-12-00543-g004.jpg

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J Endocrinol Invest. 2025 Jun 9. doi: 10.1007/s40618-025-02594-5.
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本文引用的文献

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A Prospective Comparative Study on Cardiac Alterations After Surgery and Drug Treatment of Primary Aldosteronism.原发性醛固酮增多症术后与药物治疗后心脏改变的前瞻性对比研究。
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Multimodality imaging in patients with heart failure and preserved ejection fraction: an expert consensus document of the European Association of Cardiovascular Imaging.射血分数保留的心力衰竭患者的多模态成像:欧洲心血管影像协会专家共识文件
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Advanced imaging tools for evaluating cardiac morphological and functional impairment in hypertensive disease.
降压药物洗脱前醛固酮与肾素比值在原发性醛固酮增多症筛查中的作用。
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RUNX1 facilitates heart failure progression through regulating TGF-β-induced cardiac remodeling.RUNX1 通过调节 TGF-β 诱导的心脏重构促进心力衰竭的进展。
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The impact of different left ventricular geometric patterns on right ventricular deformation and function in the elderly with hypertension: A two-dimensional speckle tracking and three-dimensional echocardiographic study.不同左心室几何形态对老年高血压患者右心室变形及功能的影响:二维斑点追踪及三维超声心动图研究
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