苯二氮䓬类药物对精神运动表现的影响。
Effects of benzodiazepines on psychomotor performance.
作者信息
Wittenborn J R
出版信息
Br J Clin Pharmacol. 1979;7 Suppl 1(Suppl 1):61S-67S. doi: 10.1111/j.1365-2125.1979.tb04667.x.
Abstract
1 The literature relating to the effects of benzodiazepines on psychomotor performance is critically reviewed. 2 The multiple and diverse psychomotor tests used are assessed according to their ability to demonstrate differences between drugs. 3 Three general conclusions are: (1) The speed with which simple acts of a repetitive nature are performed may be impaired by benzodiazepines. (2) learning and immediate memory will also be impaired. (3) there is relatively little indication that well established higher mental faculties are adversely involved.
摘要
- 对有关苯二氮䓬类药物对精神运动表现影响的文献进行了批判性综述。2. 根据其显示药物差异的能力，对所使用的多种不同的精神运动测试进行了评估。3. 得出三个总体结论：(1) 苯二氮䓬类药物可能会损害执行重复性简单行为的速度。(2) 学习和即时记忆也会受到损害。(3) 相对几乎没有迹象表明已确立的高级心理功能会受到不利影响。
相似文献
1
Effects of benzodiazepines on psychomotor performance.苯二氮䓬类药物对精神运动表现的影响。
Br J Clin Pharmacol. 1979;7 Suppl 1(Suppl 1):61S-67S. doi: 10.1111/j.1365-2125.1979.tb04667.x.
2
Clobazam. A 1.5 benzodiazepine derivative: effects upon human psychomotor performance under different levels of task reinforcement.
Arch Int Pharmacodyn Ther. 1978 Apr;232(2):261-8.
3
Comparison of five anxiolytic benzodiazepines on measures of psychomotor performance and sleep.
Neuropsychobiology. 1990;24(2):84-9. doi: 10.1159/000119466.
4
Temazepam and the perceptual-motor performance of professional footballers.
Br J Sports Med. 1985 Jun;19(2):115-8. doi: 10.1136/bjsm.19.2.115.
5
Some aspects of the effects of clobazam on human psychomotor performance.氯巴占对人类精神运动表现影响的某些方面。
Br J Clin Pharmacol. 1979;7 Suppl 1(Suppl 1):77S-82S. doi: 10.1111/j.1365-2125.1979.tb04669.x.
6
The effect of a sub-chronic administration of three dose levels of a 1,5-benzodiazepine derivative, clobazam, on subjective assessments of sleep and aspects of psychomotor performance the morning following night time medication.1,5-苯二氮䓬衍生物氯巴占三个剂量水平的亚慢性给药对夜间用药后早晨睡眠主观评估及精神运动表现各方面的影响。
Arzneimittelforschung. 1978;28(11):2169-72.
7
The effects of triazolam and nitrazepam on sleep quality, morning vigilance and psychomotor performance.三唑仑和硝西泮对睡眠质量、早晨警觉性及精神运动表现的影响。
Arzneimittelforschung. 1980;30(7):1163-6.
8
Midazolam: effects on psychomotor performance and subjective aspects of sleep and sedation in normal volunteers.咪达唑仑：对正常志愿者精神运动表现以及睡眠和镇静主观方面的影响。
Br J Clin Pharmacol. 1983;16 Suppl 1(Suppl 1):121S-126S. doi: 10.1111/j.1365-2125.1983.tb02282.x.
9
The effects of repeated doses of temazepam taken in conjunction with alcohol on aspects of psychomotor performance the morning following night time medication.
Arzneimittelforschung. 1978;28(12):2357-60.
10
Acute effects of temazepam and nitrazepam on psychomotor skills and memory.替马西泮和硝西泮对精神运动技能及记忆的急性影响。
Acta Pharmacol Toxicol (Copenh). 1979 May;44(5):364-9. doi: 10.1111/j.1600-0773.1979.tb02346.x.
引用本文的文献
1
Comparison of the effects of two amino acids, Gamma-aminobutyric acid (GABA) and L-theanine, on sedation, anxiety, and cognition in preoperative surgical patients - A randomized controlled study.两种氨基酸，γ-氨基丁酸（GABA）和L-茶氨酸，对术前手术患者镇静、焦虑和认知影响的比较——一项随机对照研究。
J Anaesthesiol Clin Pharmacol. 2025 Jan-Mar;41(1):112-118. doi: 10.4103/joacp.joacp_417_23. Epub 2024 May 8.
2
Testing a Psychological Intervention in Elite Athletes to Alleviate the Psychomotor Consequences of Doping: The Moderating Role of Personality.对精英运动员进行心理干预以减轻使用兴奋剂带来的心理运动后果：人格的调节作用。
Curr Health Sci J. 2024 Jul-Sep;50(3):392-404. doi: 10.12865/CHSJ.50.03.06. Epub 2024 Sep 30.
3
Comparison of Remimazolam versus Sevoflurane on the Postoperative Quality of Recovery in Cervical Spine Surgery: A Prospective Randomized Controlled Double-Blind Trial.瑞马唑仑与七氟醚对颈椎手术术后恢复质量的比较：一项前瞻性随机对照双盲试验
Drug Des Devel Ther. 2024 Jan 23;18:121-132. doi: 10.2147/DDDT.S441622. eCollection 2024.
4
Correlation analysis between insomnia symptoms and language function in patients with schizophrenia.精神分裂症患者失眠症状与语言功能的相关性分析
Schizophr Res Cogn. 2023 Oct 10;34:100292. doi: 10.1016/j.scog.2023.100292. eCollection 2023 Dec.
5
Evolution of benzodiazepine receptor agonist prescriptions in general practice: A registry-based study.苯二氮䓬类受体激动剂在全科医疗中的处方演变：基于登记的研究。
Front Public Health. 2022 Sep 23;10:1014734. doi: 10.3389/fpubh.2022.1014734. eCollection 2022.
6
Intraoperative Vitamin C Reduces the Dosage of Propofol in Patients Undergoing Total Knee Replacement.术中补充维生素C可减少全膝关节置换患者丙泊酚的用量。
J Pain Res. 2021 Jul 19;14:2201-2208. doi: 10.2147/JPR.S319172. eCollection 2021.
7
Remimazolam Has Low Oral Bioavailability and No Potential for Misuse in Drug-Facilitated Sexual Assaults, with or Without Alcohol: Results from Two Randomised Clinical Trials.雷米唑仑的口服生物利用度低，无论是否与酒精同时使用，都不太可能被滥用于药物辅助性侵犯：两项随机临床试验的结果。
Drugs R D. 2020 Sep;20(3):267-277. doi: 10.1007/s40268-020-00317-0.
8
Comparison of Effects of Oral Melatonin with Oral Alprazolam used as a Premedicant in Adult Patients Undergoing Various Surgical Procedures under General Anesthesia: A Prospective Randomized Placebo-Controlled Study.口服褪黑素与口服阿普唑仑作为全身麻醉下接受各种外科手术的成年患者术前用药的效果比较：一项前瞻性随机安慰剂对照研究。
Anesth Essays Res. 2018 Jul-Sep;12(3):657-662. doi: 10.4103/aer.AER_90_18.
9
Understanding the hysteresis loop conundrum in pharmacokinetic/pharmacodynamic relationships.理解药代动力学/药效动力学关系中的滞后环难题。
J Pharm Pharm Sci. 2014;17(1):34-91.
10
Melatonin in perioperative medicine: Current perspective.围手术期医学中的褪黑素：当前观点
Saudi J Anaesth. 2013 Jul;7(3):315-21. doi: 10.4103/1658-354X.115316.
本文引用的文献
1
COMPARATIVE EFFECT IN HUMAN SUBJECTS OF CHLORDIAZEPOXIDE, DIAZEPAM, AND PLACEBO ON MENTAL AND PHYSICAL PERFORMANCE.氯氮卓、地西泮和安慰剂对人体精神与身体机能影响的比较研究
Clin Pharmacol Ther. 1965 Mar-Apr;6:139-45. doi: 10.1002/cpt196562139.
2
DETERMINATION OF RED BLOOD CELL LIFE SPAN.
JAMA. 1964 Apr 27;188:375-8. doi: 10.1001/jama.1964.03060300037009.
3
THE EFFECT OF BENZQUINAMIDE, IN COMPARISON WITH CHLORDIAZEPOXIDE AND PLACEBO, ON PERFORMANCE IN SOME PSYCHOLOGICAL TESTS.与氯氮卓和安慰剂相比，苄喹酰胺对某些心理测试表现的影响。
Psychopharmacologia. 1963 Aug 20;4:402-17. doi: 10.1007/BF00403345.
4
CHLORDIAZEPOXIDE, DIPIPERON AND AMOBARBITAL. DOSE EFFECT STUDIES ON HUMAN BEINGS.氯氮卓、二哌隆与异戊巴比妥。对人体的剂量效应研究。
Psychopharmacologia. 1963 May 21;4:235-46. doi: 10.1007/BF00408179.
5
The amnesic effect of diazepam (Valium).地西泮（安定）的失忆作用。
Br J Anaesth. 1970 Aug;42(8):690-7. doi: 10.1093/bja/42.8.690.
6
Preliminary studies on the central effects of lorazepam, a new benzodiazepine.新型苯二氮䓬类药物劳拉西泮的中枢作用的初步研究。
J Clin Pharmacol New Drugs. 1971 Nov-Dec;11(6):423-7.
7
The effects of diazepam or diphenhydramine on healthy human subjects.地西泮或苯海拉明对健康人体受试者的影响。
Psychopharmacologia. 1971;21(3):202-11. doi: 10.1007/BF00403859.
8
Residual effects of hypnotics.催眠药的残留效应。
Psychopharmacologia. 1972;25(2):117-32. doi: 10.1007/BF00423189.
9
Effects of nitrazepam, amylobarbitone and placebo on some perceptual, motor and cognitive tasks in normal subjects.硝西泮、异戊巴比妥及安慰剂对正常受试者某些感知、运动和认知任务的影响。
Psychopharmacologia. 1969;14(3):167-77. doi: 10.1007/BF00404214.
10
The influence of a new chlordiazepoxide analogue on human mental and motor performance.
J Clin Pharmacol J New Drugs. 1967 Nov-Dec;7(6):330-5. doi: 10.1002/j.1552-4604.1967.tb00075.x.
Zotero 插件