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避免药物不良反应的药物遗传学。

Pharmacogenetics to Avoid Adverse Drug Reactions.

作者信息

López-Fernández Luis A

机构信息

Servicio de Farmacia, Instituto de Investigación Sanitaria Gregorio Marañón, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.

出版信息

J Pers Med. 2022 Jan 26;12(2):159. doi: 10.3390/jpm12020159.

DOI:10.3390/jpm12020159
PMID:35207648
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8879652/
Abstract

Although a cure is the main goal of a treatment, serious adverse reactions associated with these treatments are a major problem in clinical practice and cost a lot of money for health systems [...].

摘要

尽管治愈是治疗的主要目标，但与这些治疗相关的严重不良反应是临床实践中的一个主要问题，并且给卫生系统带来了高昂的成本[...]。

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J Pers Med. 2021 Nov 11;11(11):1180. doi: 10.3390/jpm11111180.
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Association of , and Phenytoin-Induced Cutaneous Adverse Drug Reactions in the South Indian Tamil Population.南印度泰米尔人群中 HLA - B*15:02、HLA - A*31:01 与苯妥英钠诱导的皮肤药物不良反应的关联
J Pers Med. 2021 Jul 28;11(8):737. doi: 10.3390/jpm11080737.
3
Genetic Determinants in and Cytochrome P450 Genes in the Risk of Aromatic Antiepileptic-Induced Severe Cutaneous Adverse Reactions.芳香族抗癫痫药物所致严重皮肤不良反应风险中的遗传决定因素及细胞色素P450基因
J Pers Med. 2021 May 7;11(5):383. doi: 10.3390/jpm11050383.
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A Pharmacogenetic Study of in Acute Coronary Syndrome Patients of Colombian Origin Reveals New Polymorphisms Potentially Related to Clopidogrel Therapy.一项针对哥伦比亚裔急性冠脉综合征患者的药物遗传学研究揭示了可能与氯吡格雷治疗相关的新多态性。
J Pers Med. 2021 May 12;11(5):400. doi: 10.3390/jpm11050400.
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J Pers Med. 2021 Mar 13;11(3):204. doi: 10.3390/jpm11030204.
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J Pers Med. 2021 Jan 11;11(1):37. doi: 10.3390/jpm11010037.
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