Department of Surgery, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal.
JNMA J Nepal Med Assoc. 2022 Feb 15;60(246):177-182. doi: 10.31729/jnma.7272.
Pancreatoduodenectomy with vascular resection is performed in locally advanced periampullary malignancies. In our practice, early oral feeding is initiated in patients undergoing pancreatoduodenectomy. This study aims to find the prevalence of early oral feeding with vascular resection among patients undergoing pancreatoduodenectomy.
This was a descriptive cross-sectional study conducted among hospital records of 152 patients who underwent pancreatoduodenectomy in the department of surgery of a tertiary care hospital from 2016 to 2020. Ethical approval was taken from the Institutional Review Committee (Reference number: 0812202102). Convenience sampling was done. Patients clinical and sociodemographic data were collected and analyzed using Statistical Package for the Social Sciences version 20. Point estimate at 95% Confidence Interval was calculated along with frequency, percentage, mean, and median.
Among 152 patients undergoing pancreatoduodenectomy, early oral feeding with vascular resection was done in 17 (11.18%) (6.17-16.19 at 95% Confidence Interval). Portal vein and superior mesenteric artery were resected in one (5.88%) and hepatic artery in one (5.88%) patient. Type I, III and IV reconstruction was done in nine (52.9%), five (29.41%) and one (5.88%) respectively. Clinically relevant delayed gastric emptying and postoperative pancreatic fistula were seen in two (11.7%). Complication of Clavien-Dindo Grade III or higher was seen in one (5.88%) patient. One (5.88%) mortality was noted.
The prevalence of early oral feeding with vascular resection among patients undergoing pancreatoduodenectomy was similar to other studies done in similar settings. Early enteral feeding is well tolerated in patients undergoing pancreatoduodenectomy with vascular resection.
胰十二指肠切除术伴血管切除用于局部晚期壶腹周围恶性肿瘤。在我们的实践中，胰十二指肠切除术后患者开始早期口服喂养。本研究旨在探讨血管切除术后胰十二指肠切除术后患者早期口服喂养的发生率。
这是一项在 2016 年至 2020 年期间在一家三级护理医院外科部门接受胰十二指肠切除术的 152 名患者的医院记录中进行的描述性横断面研究。机构审查委员会（参考号：0812202102）已获得伦理批准。采用便利抽样法。收集患者的临床和社会人口统计学数据，并使用社会科学统计软件包 20 版进行分析。计算了 95%置信区间的点估计值，以及频率、百分比、平均值和中位数。
在 152 名接受胰十二指肠切除术的患者中，17 名（11.18%）（95%置信区间为 6.17-16.19）进行了早期口服喂养伴血管切除。1 名（5.88%）患者门静脉和肠系膜上动脉被切除，1 名（5.88%）患者肝动脉被切除。分别有 9 名（52.9%）、5 名（29.41%）和 1 名（5.88%）患者进行了 I 型、III 型和 IV 型重建。2 名（11.7%）患者出现临床相关的胃排空延迟和术后胰瘘。1 名（5.88%）患者出现 Clavien-Dindo 分级 III 级或更高的并发症。1 名（5.88%）患者死亡。
在接受胰十二指肠切除术的患者中，伴血管切除的早期口服喂养的发生率与在类似环境中进行的其他研究相似。血管切除术后胰十二指肠切除术后患者早期肠内喂养耐受性良好。
