Department of Cardiothoracic and Vascular Surgery, Manmohan Cardiothoracic Vascular and Transplant Center, Maharajgunj Medical Campus, Institute of Medicine, Maharajgunj, Kathmandu, Nepal.
JNMA J Nepal Med Assoc. 2022 Feb 15;60(246):111-115. doi: 10.31729/jnma.6538.
Heart neoplasms are rare tumors. Myxoma is the commonest primary benign tumor of the heart presenting with features of obstruction, arrhythmia, and embolism. Surgical excision of the tumor is the gold standard of treatment. The aim of the study is to find out the prevalence of cardiac myxoma among all cardiac surgeries operated during the study period.
A descriptive cross-sectional study was done among 3800 patients undergoing surgery for cardiac tumors in a tertiary care center after obtaining approval from the Institutional Review Committee (Reference number- 36/(6-11)E2/077/078). The data was collected retrospectively from August 2012 to August 2020 using convenience sampling method. Statistical analysis was performed using Microsoft Excel 2016. Point estimate at 95% Confidence Interval was calculated along with frequency, percentage, mean and standard deviation.
There were 26 (0.68%) (0.42-0.94 at 95% Confidence Interval) myxoma among 3800 cardiac surgeries performed over eight years. The mean age of the patients was 54.76±14.31 (range 17-75) years. Twenty (76.92%) patients were females. The commonest presenting symptom was shortness of breath in 19 (73.07%) patients. En masse excision with the closure of the atrial septal defect was the principal surgical technique. The mean Intensive Care Unit stay and hospital stays were 2.92±1.29 and 6.26±2.61 days respectively. There was no perioperative mortality.
Cardiac myxoma was the most common cardiac tumor encountered as in other studies.
心脏肿瘤较为罕见。黏液瘤是心脏最常见的原发性良性肿瘤，其特征为阻塞、心律失常和栓塞。肿瘤切除术是治疗的金标准。本研究旨在找出研究期间所有心脏肿瘤手术中心脏黏液瘤的患病率。
在获得机构审查委员会的批准后（参考编号-36/(6-11)E2/077/078），对在三级护理中心接受心脏肿瘤手术的 3800 例患者进行了一项描述性横断面研究。数据采用便利抽样法从 2012 年 8 月至 2020 年 8 月进行回顾性收集。使用 Microsoft Excel 2016 进行统计分析。计算了 95%置信区间的点估计值以及频率、百分比、平均值和标准差。
在 8 年期间进行的 3800 例心脏手术中，有 26 例（0.68%）（95%置信区间为 0.42-0.94）黏液瘤。患者的平均年龄为 54.76±14.31 岁（范围 17-75 岁）。20 例（76.92%）患者为女性。最常见的症状是 19 例（73.07%）患者的呼吸急促。主要的手术技术是整块切除并关闭房间隔缺损。重症监护病房平均住院时间和住院时间分别为 2.92±1.29 天和 6.26±2.61 天。无围手术期死亡。
与其他研究一样，心脏黏液瘤是最常见的心脏肿瘤。
