Irjala K M, Grönroos P E
Central Laboratory, Turku University Central Hospital, Finland.
Ann Med. 1998 Jun;30(3):267-72. doi: 10.3109/07853899809005854.
The results of laboratory tests have a substantial role in the diagnostics of diseases. However, laboratory results do not always correspond with the patient's clinical status. They may be unexpected and surprising. On the other hand, an abnormal laboratory result may be accepted as such and interpreted as a sign of a disease. However, an abnormal result may result from several factors other than disease. Conventionally, these interfering factors have been divided into preanalytical and analytical factors and furthermore into factors acting in vivo and in vitro. The list of these factors is long and laborious to bear in mind. In this review we focus on the factors which, in practice, most often affect laboratory results in healthy individuals and which explain an unexpected result.
实验室检测结果在疾病诊断中起着重要作用。然而,实验室结果并不总是与患者的临床状况相符。它们可能出乎意料且令人惊讶。另一方面,异常的实验室结果可能被视为正常并被解释为疾病的迹象。然而,异常结果可能由疾病以外的多种因素导致。传统上,这些干扰因素被分为分析前和分析因素,进而又分为体内和体外作用的因素。这些因素的清单很长,难以牢记。在本综述中,我们关注的是在实际中最常影响健康个体实验室结果并解释意外结果的因素。