Elias S, Simpson J L, Martin A O, Sabbagha R, Bombard A, Rosinsky B J, Baum L D
Am J Obstet Gynecol. 1986 Jun;154(6):1349-52. doi: 10.1016/0002-9378(86)90723-4.
Among the first 150 women who agreed to have chorionic villus sampling after receiving counseling and giving informed consent, 41 proved ineligible. In six (5.5%) of the remaining 109 cases in which chorionic villus sampling was performed, we were unsuccessful in obtaining an adequate amount of villi to permit diagnostic testing. In the single loss, fetal viability was confirmed 2 weeks after sampling; however, fetal death became evident 3 weeks later. In four (3.7%) cases the pregnancies were terminated because of abnormal results, and in one (0.9%) case the pregnancy was electively terminated after normal results. Among the 41 completed pregnancies no anomalies were evident in the infants. There were two premature deliveries; one of these two infants died shortly after birth following premature rupture of the membranes at 29 weeks' gestation. All undelivered cases were progressing normally at the time of submission.
在最初150名接受咨询并签署知情同意书后同意进行绒毛取样的女性中，有41名被证明不符合条件。在剩余109例进行绒毛取样的病例中，有6例（5.5%）未能获取足够量的绒毛用于诊断检测。在唯一的一例流产病例中，取样后2周确认胎儿存活；然而，3周后胎儿死亡。在4例（3.7%）病例中，因结果异常终止妊娠，1例（0.9%）病例在结果正常后选择终止妊娠。在41例足月分娩的病例中，婴儿未发现异常。有2例早产；其中1例婴儿在孕29周胎膜早破后出生不久死亡。在提交报告时，所有未分娩病例进展正常。
