Suppr超能文献

树突状细胞及其生物活性化合物对代谢紊乱的潜在治疗作用。

Potential Therapeutic Effects of DC and Its Bioactive Compounds on Metabolic Disorders.

作者信息

Siti Hawa Nordin, Mohamed Suhaila, Kamisah Yusof

机构信息

Department of Basic Medical Sciences, Faculty of Medicine, Universiti Sultan Zainal Abidin, Kuala Terengganu 20400, Malaysia.

UPM-MAKNA Cancer Research Laboratory, Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400, Malaysia.

出版信息

Pharmaceuticals (Basel). 2022 Jan 29;15(2):167. doi: 10.3390/ph15020167.

Abstract

Metabolic disorders like diabetes mellitus, hypertension, dyslipidemia, and obesity are major medical problems globally. The incidence of these disorders has increased tremendously in recent years. Studies have demonstrated that plants with antioxidant and anti-inflammatory properties have beneficial effects on these disorders. One of these plants is DC, commonly known as kaffir lime. This review aims to present updates on the progress of research regarding the use of in metabolic disorders. Phytochemical compounds, including β-pinene, sabinene, citronellal, and citronellol, have been detected in the plant; and its extract exhibited potential antidiabetic, antihyperlipidemic and anti-obesity activity, as well as prevention of development of hypertension. These beneficial properties may be attributable to the presence of bioactive compounds which have therapeutic potential in treating these metabolic disorders. The compounds have the potential to be developed as candidate drugs. This review will assist in validating the regulatory role of the extract and its bioactive compounds on metabolic disorders, thus expediting future research in the area.

摘要

糖尿病、高血压、血脂异常和肥胖等代谢紊乱是全球主要的医学问题。近年来,这些疾病的发病率大幅上升。研究表明,具有抗氧化和抗炎特性的植物对这些疾病有有益影响。其中一种植物是DC,俗称青柠。本综述旨在介绍有关DC在代谢紊乱中应用的研究进展。该植物中已检测到包括β-蒎烯、桧烯、香茅醛和香茅醇在内的植物化学化合物;其提取物具有潜在的抗糖尿病、抗高血脂和抗肥胖活性,以及预防高血压发展的作用。这些有益特性可能归因于生物活性化合物的存在,这些化合物在治疗这些代谢紊乱方面具有治疗潜力。这些化合物有可能被开发为候选药物。本综述将有助于验证提取物及其生物活性化合物对代谢紊乱的调节作用,从而加快该领域的未来研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b72/8875002/57c90cb647d0/pharmaceuticals-15-00167-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验