Schachter H
Biochem Cell Biol. 1986 Mar;64(3):163-81. doi: 10.1139/o86-026.
Detailed studies on the enzyme machinery responsible for the biosynthesis of protein-bound oligosaccharides of the Asn-GlcNAc and Ser(Thr)-GalNAc linkage types have allowed the formulation of some general rules which explain, at least in part, the branching patterns and microheterogeneity of these structures. These rules are discussed under the following headings: competition of two or more enzymes for a common substrate; controls at the level of enzyme substrate specificity (e.g., critical sugar residues which turn enzyme activity on or off, branch specificity, and the role of the polypeptide in the glycoprotein substrate); substrate availability.
对负责天冬酰胺 - N - 乙酰葡糖胺和丝氨酸（苏氨酸） - N - 乙酰半乳糖胺连接类型的蛋白质结合寡糖生物合成的酶机制进行的详细研究，已得出一些通用规则，这些规则至少部分解释了这些结构的分支模式和微观异质性。这些规则将在以下标题下进行讨论：两种或更多种酶对共同底物的竞争；酶底物特异性水平的控制（例如，开启或关闭酶活性的关键糖残基、分支特异性以及糖蛋白底物中多肽的作用）；底物可用性。
