Institute for Global Food Security, Queen's University, Belfast BT7 1NN, United Kingdom.
DSM Nutritional Products, Kaiseraugst 4303, Switzerland.
Poult Sci. 2022 Apr;101(4):101746. doi: 10.1016/j.psj.2022.101746. Epub 2022 Jan 22.
A systematic review and meta-analysis was conducted to investigate the role of Eimeria species, dose and inoculation time, on performance and infection outcomes of different broiler strains infected for different study durations. The meta-analysis addressed E. acervulina, E. maxima, E. tenella, and mixed species infections, and involved data from 72 peer-reviewed articles, corresponding to 521 treatments performed on 20,756 broilers. A secondary objective was to investigate the effects of synthetic anticoccidials, ionophores, and vaccination against Eimeria on the above outcomes. Performance during infection was scaled (%) to that of the uninfected birds. Infection reduced scaled ADFI and ADG (P < 0.001) and increased feed conversion ratio (FCR; P < 0.05); there was a significant interaction between dose and species on scaled ADFI and ADG, suggesting that different species affected these variables to different extents (P < 0.001). There was a tendency for an interaction between dose and broiler strain on scaled ADFI (P = 0.079), and a significant interaction between these variables on scaled ADG (P < 0.01). A tendency for an interaction between oocyst dose and Eimeria species (P = 0.067) on maximum number of oocysts excreted was observed. Lesion scores were significantly affected by dose, species, and their interaction (P < 0.05), the latter caused by an increase in the lesion scores during E. maxima and E. tenella infections. Control methods significantly affected scaled ADG and FCR (P < 0.05) and there was an interaction between dose and control methods on ADFI (P < 0.001). Synthetic anticoccidial use improved scaled ADG (P < 0.01), whereas ionophores improved FCR compared with untreated birds (P < 0.01). An interaction between dose and control method on scaled ADFI was caused by the higher ADFI of vaccinated compared to untreated birds, as dose increased. There was a significant effect of control methods on lesion scores (P < 0.01). All findings advance our understanding of the factors that influence the impact of coccidiosis and its controls in broilers.
进行了系统评价和荟萃分析，以研究艾美耳球虫种、剂量和接种时间对不同肉鸡品种在不同研究时间内感染的性能和感染结果的影响。荟萃分析涉及艾美尔属球虫种（E. acervulina、E. maxima、E. tenella 和混合种感染），涉及 72 篇同行评议文章的数据，对应于 20756 只肉鸡的 521 次处理。次要目标是研究合成抗球虫药、离子载体和疫苗接种对上述结果的影响。感染期间的性能以感染鸟类的百分比表示。感染降低了感染鸡的标准化采食量（ADFI）和平均日增重（ADG）（P<0.001），增加了饲料转化率（FCR；P<0.05）；剂量和种间对标准化 ADFI 和 ADG 有显著的相互作用，表明不同的种对这些变量的影响程度不同（P<0.001）。在标准化 ADFI 方面，剂量和肉鸡品种之间存在相互作用的趋势（P=0.079），在标准化 ADG 方面，这些变量之间存在显著的相互作用（P<0.01）。在排出的卵囊数量上，观察到卵囊剂量和艾美尔球虫种之间相互作用的趋势（P=0.067）。病变评分显著受剂量、种和它们的相互作用影响（P<0.05），后者是由于在 E. maxima 和 E. tenella 感染期间病变评分增加所致。控制方法显著影响标准化 ADG 和 FCR（P<0.05），剂量和控制方法之间存在 ADFI 的相互作用（P<0.001）。与未处理的鸟类相比，使用合成抗球虫药提高了标准化 ADG（P<0.01），而离子载体则提高了 FCR（P<0.01）。剂量和控制方法之间在标准化 ADFI 上的相互作用是由于接种的鸡比未处理的鸡的 ADFI 更高，随着剂量的增加。控制方法对病变评分有显著影响（P<0.01）。所有发现都提高了我们对影响球虫病及其在肉鸡中控制的因素的理解。
