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改善震颤患者的功能障碍:辅助技术的疗效、考虑因素和挑战的临床视角。

Improving functional disability in patients with tremor: A clinical perspective of the efficacies, considerations, and challenges of assistive technology.

机构信息

Chulalongkorn Centre of Excellence for Parkinson's Disease & Related Disorders, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok 10330, Thailand; The Academy of Science, The Royal Society of Thailand, Bangkok 10330, Thailand.

Chulalongkorn Centre of Excellence for Parkinson's Disease & Related Disorders, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok 10330, Thailand.

出版信息

J Neurol Sci. 2022 Apr 15;435:120197. doi: 10.1016/j.jns.2022.120197. Epub 2022 Feb 19.

DOI:10.1016/j.jns.2022.120197
PMID:35220112
Abstract

Despite advances in treatments for tremor disorders, many patients are still left with functional disability affecting both basic and complex tasks needed for independent living, reflecting a significant gap in the current management of tremor disorders. Assistive devices present a possible solution to bridge the gap between symptom burden and current therapies, offering safe and effective tremor suppression. Although not yet considered as an option in most therapeutic guidelines for tremor disorders, assistive technologies (AT) offer a unique opportunity as adjunctive interventions utilising new portable technologies at lower cost, with minimal adverse effects. Here, the clinical concept of Human Activity Assistive Technology model via two groups of AT (limb weights and handheld devices; orthoses and exoskeletons) in patients with tremor is reviewed, supported by clinical evidence on reduction of tremor severity or improved functional performance. Although most devices are prototypes with limited clinical evidence, many are approved as medical devices and are commercially available. However, despite increased availability of these devices, there are still barriers to their adoption, mostly influenced by perceptions on privacy, trust, and functionality/added value. Long-term adherence to these devices is also unknown. In order to promote accessibility and usability of AT for tremor, an evaluation consensus by an interdisciplinary team (users, prescribers, and technicians) is required to identify those in need and to offer device recommendations. Future developments of AT for tremor should improve user comfort by incorporating softer, lightweight materials and explore new mechanisms to enhance wearability and long-term efficacies. This article is part of the Special Issue "Tremor" edited by Daniel D. Truong, Mark Hallett, and Aasef Shaikh.

摘要

尽管在治疗震颤障碍方面取得了进展,但许多患者仍存在功能障碍,影响了独立生活所需的基本和复杂任务,这反映了当前震颤障碍管理方面的重大差距。辅助设备为弥合症状负担和当前治疗之间的差距提供了一种可能的解决方案,提供了安全有效的震颤抑制。尽管在大多数震颤障碍治疗指南中尚未将其视为一种选择,但辅助技术 (AT) 提供了一个独特的机会,可作为利用新的便携式技术以更低成本、最小不良反应的附加干预措施。在这里,通过两组 AT(肢体重量和手持设备;矫形器和外骨骼)来回顾震颤患者的人体活动辅助技术模型的临床概念,同时还提供了关于减轻震颤严重程度或改善功能表现的临床证据。尽管大多数设备都是原型,临床证据有限,但许多设备已被批准为医疗器械并可在商业上获得。然而,尽管这些设备的可用性有所增加,但它们的采用仍然存在障碍,主要受到对隐私、信任和功能/附加值的看法的影响。这些设备的长期依从性也未知。为了促进震颤辅助技术的可及性和可用性,需要由跨学科团队(用户、处方者和技术人员)进行评估共识,以确定需要的人员,并提供设备建议。未来的震颤辅助技术的发展应通过采用更柔软、更轻的材料来提高用户舒适度,并探索新的机制来提高佩戴舒适性和长期疗效。本文是由 Daniel D. Truong、Mark Hallett 和 Aasef Shaikh 编辑的“震颤”特刊的一部分。

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