Department of Urology, University of Michigan, Medical Science I, 1137 Catherine Street, 4432, Ann Arbor, MI, 48109-5330, USA.
Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
World J Urol. 2022 Jun;40(6):1575-1580. doi: 10.1007/s00345-022-03967-8. Epub 2022 Feb 27.
High-power laser lithotripsy can elevate temperature within the urinary collecting system and increase risk of thermal injury. Temperature elevation is dependent on power settings and operator duty cycle (ODC)-the percentage of time the laser pedal is depressed. The objective of this study was to quantify temperature and thermal dose resulting from laser activation at different ODC in an in-vitro model.
Holmium laser energy (1800 J) was delivered at 30 W (0.5 J × 60 Hz) to a fluid filled glass bulb. Room temperature irrigation was applied at 8 ml/min. ODC was evaluated in 10% increments from 50-100%. Bulb fluid temperature was recorded and thermal dose calculated. Time to reach threshold of thermal injury and maximal allowable energy were also determined at each ODC.
Upon laser activation, there was an immediate rise in fluid temperature with a "saw-tooth" oscillation superimposed on the curves for 50-90% ODC corresponding to periodic activation of the laser. Higher ODC resulted in greater maximum temperature and thermal dose, with ODC ≥ 70% exceeding threshold. Use of 50% compared to 60% ODC resulted in a tenfold increase in time required to reach threshold of thermal injury and an eightfold increase in maximal allowable energy.
Laser activation at higher ODC produced greater fluid temperature and thermal dose. Time to threshold of thermal injury and maximal allowable energy were dramatically higher for 50% compared to 60% ODC at high-power settings. Proper management of laser ODC can enhance patient safety and optimize stone treatment.
高能激光碎石术会使尿路收集系统内的温度升高,增加热损伤的风险。温度升高取决于功率设置和操作人员的工作周期(ODC),即激光脚踏板按下的时间百分比。本研究的目的是在体外模型中定量研究不同 ODC 下激光激活导致的温度和热剂量。
将钬激光能量(1800J)以 30W(0.5J×60Hz)输送到充满液体的玻璃灯泡中。室温灌溉以 8ml/min 的速度应用。ODC 以 10%的增量评估,范围为 50-100%。记录灯泡内液体温度并计算热剂量。还在每个 ODC 下确定达到热损伤阈值和最大允许能量所需的时间。
激光激活后,液体温度立即升高,50-90%ODC 的曲线呈现出“锯齿”波动,这对应于激光的周期性激活。较高的 ODC 导致更高的最大温度和热剂量,ODC≥70%超过阈值。与使用 60%ODC 相比,使用 50%ODC 会使达到热损伤阈值所需的时间增加十倍,并使最大允许能量增加八倍。
更高的 ODC 下的激光激活会产生更高的液体温度和热剂量。在高功率设置下,与 60%ODC 相比,50%ODC 时达到热损伤阈值和最大允许能量的时间显著增加。适当管理激光 ODC 可以提高患者安全性并优化结石治疗效果。