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输尿管镜碎石术中激光激发模式:对肾盏内液温度和热剂量的影响。

Patterns of Laser Activation During Ureteroscopic Lithotripsy: Effects on Caliceal Fluid Temperature and Thermal Dose.

机构信息

Department of Urology and University of Michigan, Ann Arbor, Michigan, USA.

Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.

出版信息

J Endourol. 2021 Aug;35(8):1217-1222. doi: 10.1089/end.2020.1067. Epub 2021 Feb 3.

Abstract

Characterizing patterns of laser activation is important for assessing thermal dose during laser lithotripsy. The objective of this study was twofold: first, to quantify the range of operator duty cycle (ODC) and pedal activation time during clinical laser lithotripsy procedures, and second, to determine thermal dose in an caliceal model when 1200 J of energy was applied with different patterns of 50% ODC for 60 seconds. Data from laser logs of ureteroscopy cases performed over a 3-month period were used to calculate ODC (lasing time/lithotripsy time). Temporal and rolling 1-minute average power tracings were generated for each case. experiments were conducted using a 21 mm diameter glass bulb in a 37°C water bath, simulating a renal calix. A LithoVue ureteroscope with attached thermocouple was inserted and 8 mL/min irrigation was delivered with a 242 μm laser fiber within the working channel. In total, 1200 J of laser energy was applied in five different patterns at 20 W average power for 60 seconds. Thermal dose was calculated using the Sapareto and Dewey method. A total of 63 clinical cases were included in the analysis. Mean ODC was 32% overall and 63% during the 1-minute of greatest energy delivery. Mean time of pedal activation was 3.6 seconds. studies revealed longer pedal activation times produced higher peak temperature and thermal dose. Thermal injury threshold was reached in 9 seconds when 40 W was applied at 50% ODC with laser activation patterns of 30 seconds on/off and 15 seconds on/off. ODC was quantified from clinical laser lithotripsy cases: 32% overall and 63% during 1-minute of peak power. Time of pedal activation is an important factor contributing to fluid heating and thermal dose. Awareness of these concepts is necessary to reduce risk of thermal injury during laser lithotripsy procedures.

摘要

描述激光激发模式对于评估激光碎石术中的热剂量非常重要。本研究的目的有两个:首先,量化临床激光碎石术中操作人员的占空比(ODC)和脚踏激活时间范围;其次,当以 50% ODC 施加 60 秒,以不同模式施加 1200J 能量时,确定肾盏模型中的热剂量。使用在三个月期间进行的输尿管镜检查病例的激光日志数据来计算 ODC(激光时间/碎石时间)。为每个病例生成时间和滚动 1 分钟平均功率跟踪。实验在 37°C 水浴中的 21mm 直径玻璃灯泡中进行,模拟肾盏。将带有热电偶的 LithoVue 输尿管镜插入工作通道内,以 242μm 的激光光纤以 8mL/min 的速度输送冲洗液。总共以 20W 的平均功率在五个不同模式下施加 1200J 的激光能量,持续 60 秒。使用 Sapareto 和 Dewey 方法计算热剂量。共有 63 例临床病例纳入分析。总 ODC 平均为 32%,在最大能量输送的 1 分钟内为 63%。脚踏激活的平均时间为 3.6 秒。研究表明,更长的脚踏激活时间会产生更高的峰值温度和热剂量。当以 50% ODC 施加 40W 且激光激活模式为 30 秒 ON/30 秒 OFF 和 15 秒 ON/15 秒 OFF 时,达到 9 秒时达到热损伤阈值。从临床激光碎石术病例中量化了 ODC:总共有 32%,在 1 分钟最大功率时为 63%。脚踏激活时间是导致流体加热和热剂量的重要因素。了解这些概念对于降低激光碎石术过程中热损伤的风险是必要的。

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