Yuk Young Sam, Choi Jae Eun, Kim Jae Kyung
Department of Clinical Medical Science, Dankook University Graduate School of Health and Welfare, Cheonan, Republic of Korea.
Department of Public Health Science, Dankook University Graduate School, Cheonan, Republic of Korea.
Iran J Microbiol. 2021 Dec;13(6):779-784. doi: 10.18502/ijm.v13i6.8079.
and are the most common causative agents of bacterial vaginosis, and infections with these pathogens lead to inflammation, endometritis, and pruritus. The aim of this retrospective study was to determine the trends of infections based on real-time PCR data according to age and sex in patients with sexually transmitted diseases.
A total of 59,381 specimens isolated at a clinical laboratory from September 2018 to December 2020 were subjected to real-time PCR for the detection of DNA. Sample types included catheter, pus, tissue, swab, and urine samples.
Among 59,381 samples, 20,718 (34.8%) were positive for . Of the positive samples, 13,186 (63.7%) were from male patients and 7,532 (36.3%) were from female patients. Average patient age was 39.1 years (the average age of male and female patients was 38.34 and 40.43 years, respectively). Female patients younger than 19 years exhibited the highest incidence of , at 71.57%, followed by 68.46% incidence in those aged 20-29 years; the lowest incidence was in women aged 40-49 years. Further, among specimen types, the highest number of -positive specimens was obtained by the swab sampling method.
From 2018 to 2020 in Korea, the number of tests conducted for bacterial vaginosis has increased, while the incidence of infections appears to have decreased. the finding that female adolescents have a high tendency to carry the pathogen is important. and for effective surveillance of BV, sampling by cotton swabs and detection by multiplex PCR might be a good approach.
[具体病原体1]和[具体病原体2]是细菌性阴道病最常见的病原体，这些病原体感染会导致炎症、子宫内膜炎和瘙痒。这项回顾性研究的目的是根据性传播疾病患者的年龄和性别，基于实时聚合酶链反应（PCR）数据确定[具体病原体]感染的趋势。
2018年9月至2020年12月期间，在一家临床实验室分离出的总共59381份标本接受了实时PCR检测，以检测[具体病原体]的DNA。样本类型包括导管、脓液、组织、拭子和尿液样本。
在59381份样本中，20718份（34.8%）[具体病原体]检测呈阳性。在阳性样本中，13186份（63.7%）来自男性患者，7532份（36.3%）来自女性患者。患者平均年龄为39.1岁（男性和女性患者的平均年龄分别为38.34岁和40.43岁）。19岁以下的女性患者[具体病原体]感染发病率最高，为71.57%，其次是20 - 29岁年龄段的发病率为68.46%；发病率最低的是40 - 49岁的女性。此外，在样本类型中，拭子采样法获得的[具体病原体]阳性标本数量最多。
2018年至2020年在韩国，细菌性阴道病的检测数量有所增加，而[具体病原体]感染的发病率似乎有所下降。女性青少年携带该病原体的倾向较高这一发现很重要。对于有效监测细菌性阴道病，棉拭子采样和多重PCR检测可能是一种不错的方法。
