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中国赣州颗粒物污染浓度与高血压住院人数之间的关联

Association between Particulate Matter Pollution Concentration and Hospital Admissions for Hypertension in Ganzhou, China.

作者信息

Li Chenwei, Zhou Xinye, Huang Kun, Zhang Xiaokang, Gao Yanfang

机构信息

School of Public Health and Health Management, Gannan Medical University, Jiangxi 34100, China.

出版信息

Int J Hypertens. 2022 Feb 17;2022:7413115. doi: 10.1155/2022/7413115. eCollection 2022.

Abstract

Fine particulate matter (PM) and respirable particulate matter (PM) are two major air pollutants with toxic effects on the cardiovascular system. Hypertension, as a chronic noncommunicable cardiovascular disease, is also a risk factor for several diseases. We applied generalized linear models with a quasi-Poisson link to assess the effect of air pollution exposure on the number of daily admissions for patients with hypertension. In addition, we established a two-pollutant model to evaluate PM and PM hazard effect stability by adjusting the other gaseous pollutants. Results showed that during the study period, 24 h mean concentrations of ambient PM and PM at 38.17 and 59.84 g/m, respectively, and a total of 2,611 hypertension hospital admissions were recorded. Air pollution concentrations significantly affected the number of hospitalizations for hypertension approximately 2 months after exposure. For each 10 g/m increase in PM and PM in single-pollutant models, the number of hospitalizations for hypertension increased by 7.92% (95% CI: 5.48% to 10.42%) and 4.46% (95% CI: 2.86% to 5.65%), respectively, at the lag day with the strongest effect. NO, O, CO, and SO had different significant effects on the number of hospitalizations over the same time period, and PM and PM still showed robust significant effects after adjustment of gas pollutants through a two-pollutant model. These findings may contribute to a better understanding of the health effects of ambient particulate matter.

摘要

细颗粒物(PM)和可吸入颗粒物(PM)是两种对心血管系统具有毒性作用的主要空气污染物。高血压作为一种慢性非传染性心血管疾病,也是多种疾病的危险因素。我们应用具有拟泊松链接的广义线性模型来评估空气污染暴露对高血压患者每日住院人数的影响。此外,我们建立了双污染物模型,通过调整其他气态污染物来评估PM和PM的危害效应稳定性。结果显示,在研究期间,环境PM和PM的24小时平均浓度分别为38.17和59.84μg/m,共记录了2611例高血压住院病例。空气污染浓度在暴露后约2个月对高血压住院人数有显著影响。在单污染物模型中,PM和PM每增加10μg/m,在效应最强的滞后日,高血压住院人数分别增加7.92%(95%CI:5.48%至10.42%)和4.46%(95%CI:2.86%至5.65%)。NO、O、CO和SO在同一时期对住院人数有不同的显著影响,通过双污染物模型调整气态污染物后,PM和PM仍显示出强烈的显著影响。这些发现可能有助于更好地理解环境颗粒物对健康的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88d2/8872648/830386f69617/ijhy2022-7413115.001.jpg

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