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住院COVID-19患者的长期新冠:一项回顾性队列研究。

Long COVID in Hospitalized COVID-19 Patients: A Retrospective Cohort Study.

作者信息

Yaksi Nese, Teker Ayse Gulsen, Imre Ayfer

机构信息

Nigde Community Health Center, Nigde, Turkey.

Department of Public Health, School of Medicine, Marmara University, Istanbul, Turkey.

出版信息

Iran J Public Health. 2022 Jan;51(1):88-95. doi: 10.18502/ijph.v51i1.8297.

Abstract

BACKGROUND

We aimed to evaluate the Long COVID frequency, and related factors in patients followed up after hospitalization.

METHODS

This retrospective cohort study included 133 inpatients with COVID-19 PCR test positivity from Nigde Province, Turkey between 01.01.2021 and 28.02.2021. The characteristics of the patients were recorded by examining the files, and the symptom questioning was made by telephone interviewing with the patients approximately four months after the date of diagnosis. The presence of at least one symptom lasting more than four weeks was described as Long COVID.

RESULTS

The frequency of Long COVID was 64.7%. The most common Long COVID symptoms were fatigue (45.9%), respiratory distress (25.6%), and muscle / joint pain (24.8%), respectively. In comparison analysis to identify factors associated with Long COVID; Long COVID was found to be more frequent among women (=0.04); patients with severe COVID-19 (<0.01), patients with prolonged hospital stay (=0.03), patients with the comorbid disease (=0.03), and Diabetes Mellitus patients (=0.02). Additionally, the frequency of Long COVID increased as the depression score stated by the person increased after COVID-19 disease (=0.02).

CONCLUSION

The treatment of COVID-19 patients should not end when they are discharged from the hospital. On the contrary, these patients, especially high-risk patients, should be followed up in post-COVID clinics and rehabilitated physically and psychosocially with a multidisciplinary approach following the recovery period of the acute illness.

摘要

背景

我们旨在评估住院后随访患者的新冠后综合征发生率及相关因素。

方法

这项回顾性队列研究纳入了2021年1月1日至2021年2月28日期间来自土耳其尼代省的133例新冠病毒核酸检测呈阳性的住院患者。通过查阅病历记录患者的特征,并在诊断日期约四个月后通过电话访谈对患者进行症状询问。持续至少四周的至少一种症状的存在被描述为新冠后综合征。

结果

新冠后综合征的发生率为64.7%。最常见的新冠后综合征症状分别为疲劳(45.9%)、呼吸急促(25.6%)和肌肉/关节疼痛(24.8%)。在确定与新冠后综合征相关因素的比较分析中;发现女性中新冠后综合征更为常见(=0.04);重症新冠患者(<0.01)、住院时间延长的患者(=0.03)、患有合并症的患者(=0.03)和糖尿病患者(=0.02)。此外,新冠后综合征的发生率随着新冠疾病后患者抑郁评分的增加而增加(=0.02)。

结论

新冠患者出院时治疗不应结束。相反,这些患者,尤其是高危患者,应在新冠后诊所进行随访,并在急性疾病恢复期后采用多学科方法进行身心康复。

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