人白细胞干扰素治疗癌症患儿水痘：一项初步对照试验。
Human leukocyte interferon in the treatment of varicella in children with cancer: a preliminary controlled trial.
作者信息
Arvin A M, Feldman S, Merigan T C
出版信息
Antimicrob Agents Chemother. 1978 Apr;13(4):605-7. doi: 10.1128/AAC.13.4.605.
Abstract
Eighteen patients who developed varicella while being treated for malignancy received human leukocyte interferon in a randomized double-blind placebo-controlled trial. Complications of varicella occurred in six of nine placebo recipients, but in only two of nine interferon recipients. Interferon was tolerated without significant side effects.
摘要
18名在接受恶性肿瘤治疗期间患水痘的患者，在一项随机双盲安慰剂对照试验中接受了人白细胞干扰素治疗。9名接受安慰剂的患者中有6人出现了水痘并发症，而9名接受干扰素的患者中只有2人出现并发症。干扰素耐受性良好，无明显副作用。
相似文献
1
Human leukocyte interferon in the treatment of varicella in children with cancer: a preliminary controlled trial.人白细胞干扰素治疗癌症患儿水痘：一项初步对照试验。
Antimicrob Agents Chemother. 1978 Apr;13(4):605-7. doi: 10.1128/AAC.13.4.605.
2
Human leukocyte interferon for the treatment of varicella in children with cancer.人白细胞干扰素治疗患癌儿童的水痘。
N Engl J Med. 1982 Apr 1;306(13):761-5. doi: 10.1056/NEJM198204013061301.
3
4
Acyclovir treatment of varicella in otherwise healthy children.阿昔洛韦对健康儿童水痘的治疗
J Pediatr. 1990 Apr;116(4):633-9. doi: 10.1016/s0022-3476(05)81618-x.
5
Short-course human leukocyte interferon in treatment of herpes zoster in patients with cancer.短疗程人白细胞干扰素治疗癌症患者的带状疱疹
Antimicrob Agents Chemother. 1981 Jan;19(1):193-5. doi: 10.1128/AAC.19.1.193.
6
Human leukocyte interferon for the treatment of herpes zoster in patients with cancer.人白细胞干扰素用于治疗癌症患者的带状疱疹。
N Engl J Med. 1978 May 4;298(18):981-7. doi: 10.1056/NEJM197805042981801.
7
Acyclovir therapy of chickenpox in immunosuppressed children--a collaborative study.免疫抑制儿童水痘的阿昔洛韦治疗——一项合作研究。
J Pediatr. 1982 Oct;101(4):622-5. doi: 10.1016/s0022-3476(82)80725-7.
8
A controlled trial of acyclovir for chickenpox in normal children.阿昔洛韦治疗正常儿童水痘的对照试验。
N Engl J Med. 1991 Nov 28;325(22):1539-44. doi: 10.1056/NEJM199111283252203.
9
Treatment of chickenpox in immunocompromised children.免疫功能低下儿童的水痘治疗
Am J Med. 1988 Aug 29;85(2A):94-5.
10
Controlled clinical trial of prophylactic human-leukocyte interferon in renal transplantation. Effects on cytomegalovirus and herpes simplex virus infections.预防性人白细胞干扰素在肾移植中的对照临床试验。对巨细胞病毒和单纯疱疹病毒感染的影响。
N Engl J Med. 1979 Jun 14;300(24):1345-9. doi: 10.1056/NEJM197906143002401.
引用本文的文献
1
Chapter 3 Antiviral drugs: general considerations.第3章 抗病毒药物：一般考虑因素。
Perspect Med Virol. 1985;1:93-126. doi: 10.1016/S0168-7069(08)70011-9. Epub 2008 May 29.
2
Interferons as Therapy for Viral and Neoplastic Diseases: From Panacea to Pariah to Paragon.干扰素作为病毒和肿瘤疾病的治疗方法：从万灵药到弃儿再到典范。
Pharmaceuticals (Basel). 2009 Dec 15;2(3):206-216. doi: 10.3390/ph2030206.
3
Treatment of hepatitis C infections with interferon: a historical perspective.干扰素治疗丙型肝炎感染：历史视角。
Hepat Res Treat. 2010;2010:323926. doi: 10.1155/2010/323926. Epub 2010 Sep 6.
4
Clinical uses of interferons.干扰素的临床应用。
Br J Clin Pharmacol. 2008 Feb;65(2):158-62. doi: 10.1111/j.1365-2125.2007.03055.x. Epub 2007 Dec 7.
5
Current pharmacological approaches to the therapy of varicella zoster virus infections: a guide to treatment.水痘带状疱疹病毒感染治疗的当前药理学方法：治疗指南
Drugs. 1999 Feb;57(2):187-206. doi: 10.2165/00003495-199957020-00005.
6
Human leukocyte interferon-alpha in cream for the management of genital herpes in Asian women: a placebo-controlled, double-blind study.人白细胞α干扰素乳膏用于治疗亚洲女性生殖器疱疹：一项安慰剂对照双盲研究。
J Mol Med (Berl). 1995 Mar;73(3):141-4. doi: 10.1007/BF00198242.
7
Advances in interferon research - Medical Staff Conference.干扰素研究进展——医务人员会议
West J Med. 1982 Mar;136(3):227-35.
8
Interferons and interferon inducers: development of clinical usefulness and therapeutic promise.干扰素与干扰素诱导剂：临床应用的发展及治疗前景
Drugs. 1982 Jan-Feb;23(1-2):37-55. doi: 10.2165/00003495-198223010-00002.
9
Antiviral agents: an update--Part 2.抗病毒药物：最新进展——第2部分。
Indian J Pediatr. 1980 Nov-Dec;47(389):515-22. doi: 10.1007/BF02822541.
10
Interferon therapy: pharmacokinetic and pharmacological aspects.干扰素治疗：药代动力学和药理学方面。
Arch Virol. 1981;67(2):121-33. doi: 10.1007/BF01318595.
本文引用的文献
1
A COMPLEMENT-FIXING ANTIGEN FOR VARICELLA-ZOSTER DERIVED FROM INFECTED CULTURES OF HUMAN FETAL DIPLOID CELLS.一种源自人胎儿二倍体细胞感染培养物的水痘-带状疱疹补体结合抗原。
Proc Soc Exp Biol Med. 1964 May;116:144-9. doi: 10.3181/00379727-116-29184.
2
Zoster immune globulin. A further assessment.带状疱疹免疫球蛋白。进一步评估。
N Engl J Med. 1974 Jan 31;290(5):243-5. doi: 10.1056/NEJM197401312900503.
3
Varicella in children with cancer: Seventy-seven cases.癌症患儿的水痘：77例病例。
Pediatrics. 1975 Sep;56(3):388-97.
4
Effect of human leukocyte interferon on hepatitis B virus infection in patients with chronic active hepatitis.人白细胞干扰素对慢性活动性肝炎患者乙型肝炎病毒感染的影响。
N Engl J Med. 1976 Sep 2;295(10):517-22. doi: 10.1056/NEJM197609022951001.
5
Adenine arabinoside therapy of herpes zoster in the immunosuppressed. NIAID collaborative antiviral study.免疫抑制患者带状疱疹的阿糖腺苷治疗。美国国立变态反应和传染病研究所协作抗病毒研究。
N Engl J Med. 1976 May 27;294(22):1193-9. doi: 10.1056/NEJM197605272942201.
Zotero 插件