促结缔组织增生性恶性黑色素瘤中的类骨质和骨形成

Osteoid and bone formation in desmoplastic malignant melanoma.

作者信息

Moreno A, Lamarca J, Martinez R, Guix M

出版信息

J Cutan Pathol. 1986 Apr;13(2):128-34. doi: 10.1111/j.1600-0560.1986.tb01513.x.

DOI:10.1111/j.1600-0560.1986.tb01513.x

Abstract

A 77-year-old man presented a recurrent subungual malignant melanoma with desmoplastic features in which heterotopic bone had developed. Histological, histochemical and immunohistochemical findings confirmed the diagnosis of malignant melanoma. Electron microscopic findings suggest that desmoplasia is the result of fibroblastic differentiation of spindle melanoma cells.

摘要

一名77岁男性出现复发性甲下恶性黑色素瘤，具有促纤维增生性特征，其中已形成异位骨。组织学、组织化学和免疫组织化学检查结果证实为恶性黑色素瘤。电子显微镜检查结果提示，促纤维增生是梭形黑色素瘤细胞成纤维细胞分化的结果。