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胰头癌行胰体尾切除术 1 年后多处胃转移

Multiple Gastric Metastases after Distal Pancreatectomy for Pancreatic Cancer.

机构信息

Department of Hepato-Biliary-Pancreatic Medicine, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Japan.

Division of Pathology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Japan.

出版信息

Intern Med. 2022 Sep 15;61(18):2741-2746. doi: 10.2169/internalmedicine.8848-21. Epub 2022 Feb 26.

DOI:10.2169/internalmedicine.8848-21
PMID:35228419
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9556238/
Abstract

A 67-year-old woman underwent distal pancreatectomy for pancreatic cancer. Recurrence in the form of lung metastasis was discovered eight months after surgery, and chemotherapy was initiated. Two years after the surgery, she was admitted for the evaluation of melena. Esophagogastroduodenoscopy revealed multiple subepithelial lesions with ulceration from the gastric body to the fornix. The histopathology of biopsy specimens was consistent with ductal adenocarcinoma, which appeared similar to the resected pancreatic cancer. The patient was diagnosed with multiple gastric metastases of pancreatic cancer. We herein report a case of pancreatic cancer with multiple gastric metastases that occurred after surgery for pancreatic tail cancer.

摘要

一位 67 岁女性因胰腺癌接受了胰体尾切除术。术后 8 个月发现肺癌转移，开始化疗。术后 2 年，因黑便入院。胃镜检查显示从胃体到穹窿部有多个黏膜下病变伴溃疡。活检标本的组织病理学检查符合导管腺癌，与切除的胰腺癌相似。患者被诊断为胰尾癌术后多发胃转移癌。本文报告一例胰体尾癌术后发生的多灶性胃转移癌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b7/9556238/dc817811810e/1349-7235-61-2741-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b7/9556238/e5b5da174cee/1349-7235-61-2741-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b7/9556238/996ac3a1aef1/1349-7235-61-2741-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b7/9556238/1437f47a4e53/1349-7235-61-2741-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b7/9556238/3b91ecb6e2db/1349-7235-61-2741-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b7/9556238/683efe259240/1349-7235-61-2741-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b7/9556238/71d1bae9e7ae/1349-7235-61-2741-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b7/9556238/dc817811810e/1349-7235-61-2741-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b7/9556238/e5b5da174cee/1349-7235-61-2741-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b7/9556238/996ac3a1aef1/1349-7235-61-2741-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b7/9556238/1437f47a4e53/1349-7235-61-2741-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b7/9556238/3b91ecb6e2db/1349-7235-61-2741-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b7/9556238/683efe259240/1349-7235-61-2741-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b7/9556238/71d1bae9e7ae/1349-7235-61-2741-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19b7/9556238/dc817811810e/1349-7235-61-2741-g007.jpg

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本文引用的文献

1
Treatment outcomes of erlotinib plus gemcitabine as late-line chemotherapy in unresectable pancreatic cancer.厄洛替尼联合吉西他滨作为不可切除胰腺癌的二线化疗的治疗结果。
Jpn J Clin Oncol. 2021 Aug 30;51(9):1416-1422. doi: 10.1093/jjco/hyab091.
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Gastric metastasis from pancreatic cancer characterized by mucosal erosion: a case report and literature review.以黏膜糜烂为特征的胰腺癌胃转移：一例报告及文献复习
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Improved prognosis of pancreatic cancer patients with peritoneal metastasis.
伴有腹膜转移的胰腺癌患者预后改善。
Pancreatology. 2021 Aug;21(5):903-911. doi: 10.1016/j.pan.2021.03.006. Epub 2021 Mar 18.
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Cancer Statistics, 2021.癌症统计数据，2021.
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A retrospective comparative study of S-IROX and modified FOLFIRINOX for patients with advanced pancreatic cancer refractory to gemcitabine plus nab-paclitaxel.吉西他滨联合白蛋白紫杉醇治疗失败的晚期胰腺癌患者采用 S-IROX 与改良 FOLFIRINOX 方案治疗的回顾性对比研究。
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Pancreatic cancer.胰腺癌。
Lancet. 2020 Jun 27;395(10242):2008-2020. doi: 10.1016/S0140-6736(20)30974-0.
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Modified FOLFIRINOX as a second-line therapy following gemcitabine plus nab-paclitaxel therapy in metastatic pancreatic cancer.转移性胰腺癌中，吉西他滨+白蛋白紫杉醇治疗后采用改良 FOLFIRINOX 作为二线治疗。
BMC Cancer. 2020 May 20;20(1):449. doi: 10.1186/s12885-020-06945-8.
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Management of Bleeding from Unresectable Gastric Cancer.不可切除胃癌出血的管理
Biomedicines. 2019 Jul 24;7(3):54. doi: 10.3390/biomedicines7030054.
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A case of successfully resected metachronous gastric and gallbladder metastases from pancreatic body cancer.一例成功切除的胰腺体部癌异时性胃和胆囊转移病例。
Surg Case Rep. 2019 Feb 13;5(1):21. doi: 10.1186/s40792-019-0581-1.
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Brain metastasis in pancreatic cancer: Two case reports.胰腺癌脑转移：两例病例报告。
Medicine (Baltimore). 2019 Jan;98(4):e14227. doi: 10.1097/MD.0000000000014227.